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Molecules 2015, 20(7), 12016-12028; doi:10.3390/molecules200712016

Studies on Chemical Composition, Antimicrobial and Antioxidant Activities of Five Thymus vulgaris L. Essential Oils

1
Department of Pharmacy, University of Salerno, Via Giovanni Paolo II, 132, Fisciano 84084, Salerno, Italy
2
Department of Ecology, Faculty of Humanities and Natural Sciences, University of Presov, 17 November street, Presov 08116, Slovak
3
Department of Industrial Engineering, University of Salerno, 1 Via Giovanni Paolo II, 132, Fisciano 84084, Salerno, Italy
4
Laboratory of Water Treatment and Reuse, Water Research and Technologies Center, Technopark of Borj-Cedria, BP 273, Soliman 8020, Tunisia
*
Author to whom correspondence should be addressed.
Academic Editor: Derek J. McPhee
Received: 8 May 2015 / Revised: 19 June 2015 / Accepted: 24 June 2015 / Published: 1 July 2015
(This article belongs to the Section Natural Products)
View Full-Text   |   Download PDF [794 KB, uploaded 1 July 2015]   |  

Abstract

This study is aimed at assessing the essential oil composition, total phenolic content, antimicrobial and antioxidant activities of Thymus vulgaris collected in five different area of the Campania Region, Southern Italy. The chemical composition of the essential oils was studied by GC-flame ionization detector (FID) and GC/MS; the biological activities were evaluated through determination of MIC and minimum bactericidal concentration (MBC) and evaluation of antioxidant activity. In total, 134 compounds were identified. The oils were mainly composed of phenolic compounds, and all oils belonged to the chemotype thymol. The antimicrobial activity of the five oils was assayed against ten bacterial strains. The oils showed different inhibitory activity against some Gram-positive pathogens. The total phenol content in the essential oils ranged from 77.6–165.1 mg gallic acid equivalents (GAE)/g. The results reported here may help to shed light on the complex chemotaxonomy of the genus Thymus. These oils could be used in many fields as natural preservatives of food and as nutraceuticals. View Full-Text
Keywords: Thymus vulgaris; essential oil; antimicrobial activity; antioxidant activity; phenolic compounds Thymus vulgaris; essential oil; antimicrobial activity; antioxidant activity; phenolic compounds
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Mancini, E.; Senatore, F.; Del Monte, D.; De Martino, L.; Grulova, D.; Scognamiglio, M.; Snoussi, M.; De Feo, V. Studies on Chemical Composition, Antimicrobial and Antioxidant Activities of Five Thymus vulgaris L. Essential Oils. Molecules 2015, 20, 12016-12028.

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