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Molecules 2015, 20(12), 21138-21156; doi:10.3390/molecules201219753

Antioxidant Phytochemicals for the Prevention and Treatment of Chronic Diseases

1
Guangdong Provincial Key Laboratory of Food, Nutrition and Health, Department of Nutrition, School of Public Health, Sun Yat-Sen University, Guangzhou 510080, China
2
School of Biological Sciences, The University of Hong Kong, Hong Kong, China
3
School of Chinese Medicine, The University of Hong Kong, Hong Kong, China
*
Author to whom correspondence should be addressed.
Academic Editor: David D. Kitts
Received: 19 August 2015 / Revised: 10 November 2015 / Accepted: 20 November 2015 / Published: 27 November 2015
(This article belongs to the Special Issue Antioxidants—A Risk-Benefit Analysis for Health)
View Full-Text   |   Download PDF [254 KB, uploaded 27 November 2015]

Abstract

Overproduction of oxidants (reactive oxygen species and reactive nitrogen species) in the human body is responsible for the pathogenesis of some diseases. The scavenging of these oxidants is thought to be an effective measure to depress the level of oxidative stress of organisms. It has been reported that intake of vegetables and fruits is inversely associated with the risk of many chronic diseases, and antioxidant phytochemicals in vegetables and fruits are considered to be responsible for these health benefits. Antioxidant phytochemicals can be found in many foods and medicinal plants, and play an important role in the prevention and treatment of chronic diseases caused by oxidative stress. They often possess strong antioxidant and free radical scavenging abilities, as well as anti-inflammatory action, which are also the basis of other bioactivities and health benefits, such as anticancer, anti-aging, and protective action for cardiovascular diseases, diabetes mellitus, obesity and neurodegenerative diseases. This review summarizes recent progress on the health benefits of antioxidant phytochemicals, and discusses their potential mechanisms in the prevention and treatment of chronic diseases. View Full-Text
Keywords: antioxidant phytochemicals; health benefits; mechanism; cardiovascular disease; cancer antioxidant phytochemicals; health benefits; mechanism; cardiovascular disease; cancer
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Zhang, Y.-J.; Gan, R.-Y.; Li, S.; Zhou, Y.; Li, A.-N.; Xu, D.-P.; Li, H.-B. Antioxidant Phytochemicals for the Prevention and Treatment of Chronic Diseases. Molecules 2015, 20, 21138-21156.

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