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Molecules 2014, 19(12), 20580-20593; doi:10.3390/molecules191220580

Au-Nanomaterials as a Superior Choice for Near-Infrared Photothermal Therapy

1
Division of Analytical Chemistry, Institute of Chemical Sciences, Bahauddin Zakariya University, Multan 60800, Pakistan
2
Institute of Analytical Chemistry and Radiochemistry, Leopold-Franzens University, Innrain 80-82. Innsbruck 6020, Austria
*
Author to whom correspondence should be addressed.
Received: 2 November 2014 / Revised: 3 December 2014 / Accepted: 4 December 2014 / Published: 9 December 2014
(This article belongs to the Special Issue Advances of Vibrational Spectroscopic Technologies in Life Sciences)
View Full-Text   |   Download PDF [1333 KB, uploaded 9 December 2014]   |  

Abstract

Photothermal therapy (PPT) is a platform to fight cancer by using multiplexed interactive plasmonic nanomaterials as probes in combination with the excellent therapeutic performance of near-infrared (NIR) light. With recent rapid developments in optics and nanotechnology, plasmonic materials have potential in cancer diagnosis and treatment, but there are some concerns regarding their clinical use. The primary concerns include the design of plasmonic nanomaterials which are taken up by the tissues, perform their function and then clear out from the body. Gold nanoparticles (Au NPs) can be developed in different morphologies and functionalized to assist the photothermal therapy in a way that they have clinical value. This review outlines the diverse Au morphologies, their distinctive characteristics, concerns and limitations to provide an idea of the requirements in the field of NIR-based therapeutics. View Full-Text
Keywords: near-infrared spectroscopy; nanoparticles/materials; therapy monitoring near-infrared spectroscopy; nanoparticles/materials; therapy monitoring
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Jabeen, F.; Najam-ul-Haq, M.; Javeed, R.; Huck, C.W.; Bonn, G.K. Au-Nanomaterials as a Superior Choice for Near-Infrared Photothermal Therapy. Molecules 2014, 19, 20580-20593.

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