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Molecules 2014, 19(12), 19491-19500; doi:10.3390/molecules191219491

Synthesis of Chiral Chalcone Derivatives Catalyzed by the Chiral Cinchona Alkaloid Squaramide

State Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Huaxi District, Guiyang 550025, China
These authors contributed equally to this work.
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Author to whom correspondence should be addressed.
Received: 3 November 2014 / Revised: 13 November 2014 / Accepted: 13 November 2014 / Published: 25 November 2014
(This article belongs to the Section Organic Synthesis)
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Abstract

An effective method has been developed for the preparation of novel chiral chalcone derivatives under mild conditions from the easily accessible starting materials nitromethane and chalcone derivatives 2. The corresponding products were obtained in moderate yields with excellent enantioselectivities (up to 99%). View Full-Text
Keywords: chalcone derivatives; enantioselective catalysis; chiral cinchona alkaloid squaramides; addition reaction chalcone derivatives; enantioselective catalysis; chiral cinchona alkaloid squaramides; addition reaction
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Xie, D.; Xie, Y.; Ding, Y.; Wu, J.; Hu, D. Synthesis of Chiral Chalcone Derivatives Catalyzed by the Chiral Cinchona Alkaloid Squaramide. Molecules 2014, 19, 19491-19500.

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