Next Article in Journal
Artificial and Natural Sialic Acid Precursors Influence the Angiogenic Capacity of Human Umbilical Vein Endothelial Cells
Previous Article in Journal
Evaluation of Selenite Effects on Selenoproteins and Cytokinome in Human Hepatoma Cell Lines
Molecules 2013, 18(3), 2563-2570; doi:10.3390/molecules18032563
Article

A New Hydroxychavicol Dimer from the Roots of Piper betle

1,2
,
3,4
,
5
,
6
 and
6,*
1 Department of Cosmetic Science, Chang Gung University of Science and Technology, Taoyuan 333, Taiwan 2 Research Center for Industry of Human Ecology, Chang Gung University of Science and Technology, Taoyuan 333, Taiwan 3 Cell Pharmacology Laboratory, Graduate Institute of Natural Products, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan 4 Chinese Herbal Medicine Research Team, Healthy Aging Research Center, Chang Gung University, Taoyuan 333, Taiwan 5 Department of Dentistry, Chang Gung Memorial Hospital, Taoyuan 333, Taiwan 6 Department of Plant Industry, National Pingtung University of Science and Technolog, Pingtung 912, Taiwan
* Author to whom correspondence should be addressed.
Received: 28 November 2012 / Revised: 8 February 2013 / Accepted: 21 February 2013 / Published: 26 February 2013
(This article belongs to the Section Natural Products)
View Full-Text   |   Download PDF [262 KB, uploaded 18 June 2014]   |   Browse Figures
SciFeed

Abstract

A new hydroxychavicol dimer, 2-(g'-hydroxychavicol)-hydroxychavicol (1), was isolated from the roots of Piper betle Linn. along with five known compounds, hydroxychavicol (2), aristololactam A II (3), aristololactam B II (4), piperolactam A (5) and cepharadione A (6). The structures of these isolated compounds were elucidated by spectroscopic methods. Compounds 1 and 2 exhibited inhibitory effects on the generation of superoxide anion and the release of elastase by human neutrophils.
Keywords: Piper betle; 2-(g'-hydroxychavicol)-hydroxychavicol; hydroxychavciol; superoxide anion; elastase; neutrophils Piper betle; 2-(g'-hydroxychavicol)-hydroxychavicol; hydroxychavciol; superoxide anion; elastase; neutrophils
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Supplementary material

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
EndNote |
RIS
MDPI and ACS Style

Lin, C.-F.; Hwang, T.-L.; Chien, C.-C.; Tu, H.-Y.; Lay, H.-L. A New Hydroxychavicol Dimer from the Roots of Piper betle. Molecules 2013, 18, 2563-2570.

View more citation formats

Related Articles

Article Metrics

For more information on the journal, click here

Comments

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert