Molecules 2013, 18(12), 15182-15192; doi:10.3390/molecules181215182
Communication

Efficient PPA-SiO2-catalyzed Synthesis of β-enaminones Under Solvent-Free Conditions

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Received: 30 September 2013; in revised form: 14 November 2013 / Accepted: 14 November 2013 / Published: 10 December 2013
(This article belongs to the Section Organic Synthesis)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: An efficient method has been developed for the synthesis of β-enaminones under solvent-free reaction conditions using PPA-SiO2 as catalyst. The reaction yields were good to excellent (up to 90%). This methodology affords high selectivity and good tolerance of a variety of different functional groups present on both aromatic and aliphatic amines. In addition, the methodology is environmentally benign and cost-effective due to absence of solvent and easy work-up.
Keywords: solvent free; 5,5-dimethylcyclohexan-1,3-dione; PPA-SiO2; β-enaminones
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MDPI and ACS Style

Nisar, M.; Ali, I.; Shah, M.R.; Qayum, M.; Zia-Ul-Haq, M.; Rashid, U.; Islam, M.S. Efficient PPA-SiO2-catalyzed Synthesis of β-enaminones Under Solvent-Free Conditions. Molecules 2013, 18, 15182-15192.

AMA Style

Nisar M, Ali I, Shah MR, Qayum M, Zia-Ul-Haq M, Rashid U, Islam MS. Efficient PPA-SiO2-catalyzed Synthesis of β-enaminones Under Solvent-Free Conditions. Molecules. 2013; 18(12):15182-15192.

Chicago/Turabian Style

Nisar, Muhammad; Ali, Ihsan; Shah, Muhammad R.; Qayum, Mughal; Zia-Ul-Haq, Muhammad; Rashid, Umer; Islam, Md. S. 2013. "Efficient PPA-SiO2-catalyzed Synthesis of β-enaminones Under Solvent-Free Conditions." Molecules 18, no. 12: 15182-15192.

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