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Molecules 2013, 18(11), 13860-13869; doi:10.3390/molecules181113860
Article

One-Pot Tandem Synthesis of 2-Arylquinazolines by a Multicomponent Cyclization Reaction

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Received: 8 October 2013; in revised form: 21 October 2013 / Accepted: 21 October 2013 / Published: 8 November 2013
(This article belongs to the Section Organic Synthesis)
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Abstract: A series of 2-arylquinazolines have been synthesized in moderate to excellent yields by one-pot tandem reaction of (2-aminophenyl)methanols, aldehydes and ceric ammonium nitrate (CAN). The utility of this transformation was demonstrated by its compatibility with a wide range of functional groups. Thus, the method represents a simple and practical procedure to access 2-arylquinazolines.
Keywords: quinazolines; multicomponent; cyclization reaction; one-pot tandem synthesis quinazolines; multicomponent; cyclization reaction; one-pot tandem synthesis
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Ye, L.; Yu, L.; Zhu, L.; Xia, X. One-Pot Tandem Synthesis of 2-Arylquinazolines by a Multicomponent Cyclization Reaction. Molecules 2013, 18, 13860-13869.

AMA Style

Ye L, Yu L, Zhu L, Xia X. One-Pot Tandem Synthesis of 2-Arylquinazolines by a Multicomponent Cyclization Reaction. Molecules. 2013; 18(11):13860-13869.

Chicago/Turabian Style

Ye, Leping; Yu, Lin; Zhu, Lijun; Xia, Xiaodong. 2013. "One-Pot Tandem Synthesis of 2-Arylquinazolines by a Multicomponent Cyclization Reaction." Molecules 18, no. 11: 13860-13869.



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