Next Article in Journal
3D-QSAR and Cell Wall Permeability of Antitubercular Nitroimidazoles against Mycobacterium tuberculosis
Previous Article in Journal
Photoaffinity Labeling of Plasma Proteins
Article Menu

Export Article

Open AccessArticle
Molecules 2013, 18(11), 13860-13869; https://doi.org/10.3390/molecules181113860

One-Pot Tandem Synthesis of 2-Arylquinazolines by a Multicomponent Cyclization Reaction

The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou 325000, Zhejiang, China
*
Author to whom correspondence should be addressed.
Received: 8 October 2013 / Revised: 21 October 2013 / Accepted: 21 October 2013 / Published: 8 November 2013
(This article belongs to the Section Organic Chemistry)
View Full-Text   |   Download PDF [256 KB, uploaded 18 June 2014]   |  

Abstract

A series of 2-arylquinazolines have been synthesized in moderate to excellent yields by one-pot tandem reaction of (2-aminophenyl)methanols, aldehydes and ceric ammonium nitrate (CAN). The utility of this transformation was demonstrated by its compatibility with a wide range of functional groups. Thus, the method represents a simple and practical procedure to access 2-arylquinazolines. View Full-Text
Keywords: quinazolines; multicomponent; cyclization reaction; one-pot tandem synthesis quinazolines; multicomponent; cyclization reaction; one-pot tandem synthesis
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
SciFeed

Share & Cite This Article

MDPI and ACS Style

Ye, L.; Yu, L.; Zhu, L.; Xia, X. One-Pot Tandem Synthesis of 2-Arylquinazolines by a Multicomponent Cyclization Reaction. Molecules 2013, 18, 13860-13869.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top