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Molecules 2013, 18(11), 13510-13519; doi:10.3390/molecules181113510
Article

Additional Minor Diterpene Glycosides from Stevia rebaudiana Bertoni

*  and
Organic Chemistry Department, The Coca-Cola Company, Global Research and Development, One Coca-Cola Plaza, Atlanta, GA 30313, USA Current address: Natural Ingredient Development, Blue California, 30111 Tomas, Rancho Santa Margarita, CA 92688, USA
* Author to whom correspondence should be addressed.
Received: 24 September 2013 / Revised: 26 October 2013 / Accepted: 28 October 2013 / Published: 31 October 2013
(This article belongs to the Section Metabolites)
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Abstract

Two additional novel minor diterpene glycosides were isolated from the commercial extract of the leaves of Stevia rebaudiana Bertoni. The structures of the new compounds were identified as 13-{β-D-glucopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→3)-β-D-glucopyranosyl-oxy} ent-kaur-16-en-19-oic acid {β-D-xylopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→3)]-O-β-D-glucupyranosyl-ester} (1), and 13-{β-D-6-deoxy-glucopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→3)-β-D-glucopyranosyl-oxy} ent-kaur-16-en-19-oic acid {β-D-glucopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→3)-β-D-gluco-pyranosyl-ester} (2), on the basis of extensive 1D (1H- and 13C-) 2D NMR (COSY, HSQC and HMBC) and MS spectroscopic data as well as chemical studies.
Keywords: Stevia rebaudiana; Compositae; Asteraceae; diterpenoid glycosides; spectral data; chemical studies; structure characterization Stevia rebaudiana; Compositae; Asteraceae; diterpenoid glycosides; spectral data; chemical studies; structure characterization
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Prakash, I.; Chaturvedula, V.S.P. Additional Minor Diterpene Glycosides from Stevia rebaudiana Bertoni. Molecules 2013, 18, 13510-13519.

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