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Molecules 2013, 18(1), 373-380; doi:10.3390/molecules18010373
Article

Two New Phragmalin-Type Limonoids from Chukrasia tabularis var. velutina

1,2,†, 2,†, 2 and 2,*
1 Testing & Analysis Center, Nanjing Normal University, Nanjing 210023, China 2 Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China These authors contributed equally to this work.
* Author to whom correspondence should be addressed.
Received: 23 October 2012 / Revised: 7 December 2012 / Accepted: 19 December 2012 / Published: 27 December 2012
(This article belongs to the Section Metabolites)
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Abstract

Two new phragmalin-type limonoids with different structural skeletons, chuktabrin K (1) and tabulalin J (2), were isolated from the stem barks of Chukrasia tabularis var. velutina in the course of our ongoing research work in this area. Compound 1 was a 16-norphragmalin with an enolic alkyl appendage at C-15, and the carbonate moiety in 1 was also rare in natural organic molecules. The basic skeleton of compound 2 was a D-ring-opened phragmalin. Their structures were elucidated on HR-ESI-MS, 1H and 13C-NMR, HSQC, HMBC, and ROESY experiments.
Keywords: phragmalin-type limonoids; 16-norphragmalin; carbonate moiety; Chukrasia tabularis var. velutina phragmalin-type limonoids; 16-norphragmalin; carbonate moiety; Chukrasia tabularis var. velutina
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Li, Y.; Luo, J.; Li, H.; Kong, L.-Y. Two New Phragmalin-Type Limonoids from Chukrasia tabularis var. velutina. Molecules 2013, 18, 373-380.

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