Two New Phragmalin-Type Limonoids from Chukrasia tabularis var. velutina

doi:10.3390/molecules18010373

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Molecules 2013, 18(1), 373-380; doi:10.3390/molecules18010373

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Two New Phragmalin-Type Limonoids from Chukrasia tabularis var. velutina

Yi Li^1,2,†, Jun Luo^2,†, Hui Li² and Ling-Yi Kong^2,*

¹ Testing & Analysis Center, Nanjing Normal University, Nanjing 210023, China ² Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China ^† These authors contributed equally to this work.

* Author to whom correspondence should be addressed.

Received: 23 October 2012; in revised form: 7 December 2012 / Accepted: 19 December 2012 / Published: 27 December 2012

(This article belongs to the Section Natural Products)

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Abstract: Two new phragmalin-type limonoids with different structural skeletons, chuktabrin K (1) and tabulalin J (2), were isolated from the stem barks of Chukrasia tabularis var. velutina in the course of our ongoing research work in this area. Compound 1 was a 16-norphragmalin with an enolic alkyl appendage at C-15, and the carbonate moiety in 1 was also rare in natural organic molecules. The basic skeleton of compound 2 was a D-ring-opened phragmalin. Their structures were elucidated on HR-ESI-MS, ¹H and ¹³C-NMR, HSQC, HMBC, and ROESY experiments.

Keywords: phragmalin-type limonoids; 16-norphragmalin; carbonate moiety; Chukrasia tabularis var. velutina

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Cite This Article

MDPI and ACS Style

Li, Y.; Luo, J.; Li, H.; Kong, L.-Y. Two New Phragmalin-Type Limonoids from Chukrasia tabularis var. velutina. Molecules 2013, 18, 373-380.

AMA Style

Li Y, Luo J, Li H, Kong L-Y. Two New Phragmalin-Type Limonoids from Chukrasia tabularis var. velutina. Molecules. 2013; 18(1):373-380.

Chicago/Turabian Style

Li, Yi; Luo, Jun; Li, Hui; Kong, Ling-Yi. 2013. "Two New Phragmalin-Type Limonoids from Chukrasia tabularis var. velutina." Molecules 18, no. 1: 373-380.

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