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Molecules 2013, 18(1), 1181-1187; doi:10.3390/molecules18011181
Article

Two Cerebrosides Isolated from the Seeds of Sterculia lychnophora and Their Neuroprotective Effect

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Received: 22 November 2012 / Revised: 25 December 2012 / Accepted: 8 January 2013 / Published: 17 January 2013
(This article belongs to the Section Metabolites)
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Abstract

Two cerebrosides named 1-O-b-D-glucopyranosyl-(2S,3R,4E,8Z)-2-[(2-hydroxyoctadecanoyl)amido]-4,8-octadecadiene-1,3-diol (1) and soya-cerebroside I (2) were isolated from the seeds of Sterculia lychnophora for the first time. Their structures were completely characterized by spectroscopic methods including IR, MS and NMR. Compound 1 exhibited moderate neuroprotective effect against SH-SY5Y cell damage induced by hydrogen peroxide.
Keywords: Sterculia lychnophora; constituents; cerebrosides; neuroprotective effect Sterculia lychnophora; constituents; cerebrosides; neuroprotective effect
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Wang, R.-F.; Wu, X.-W.; Geng, D. Two Cerebrosides Isolated from the Seeds of Sterculia lychnophora and Their Neuroprotective Effect. Molecules 2013, 18, 1181-1187.

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