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Molecules 2012, 17(9), 10414-10428; doi:10.3390/molecules170910414
Article

Synthesis, Structure and Insecticidal Activities of Some Novel Amides Containing N-Pyridylpyrazole Moeities

1,* , 2
,
2
 and
2
1 Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, Tianjin 300070, China 2 State Key Laboratory of Elemento-Organic Chemistry, National Pesticide Engineering Research Center, Nankai University, Tianjin 300071, China
* Author to whom correspondence should be addressed.
Received: 1 August 2012 / Revised: 13 August 2012 / Accepted: 18 August 2012 / Published: 31 August 2012
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Abstract

In our search for environmentally benign insecticides with high activity, low toxicity and low residue, a novel series of amides containing N-pyridylpyrazole moieties were designed and synthesized. The structures of the title compounds were characterized and confirmed by 1H-NMR and elemental analysis. Furthermore, the structure of compound 7l was determined by single crystal X-ray diffraction. The preliminary bioassay tests showed that some of them exhibited good insecticidal activities against Mythimna separata Walker, Plutella xylostella (Linnaeus, 1758) and Laphygma exigua Hübner.
Keywords: amide; N-pyridylpyrazole; synthesis; crystal structure; insecticidal activity amide; N-pyridylpyrazole; synthesis; crystal structure; insecticidal activity
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Dong, W.-L.; Xu, J.-Y.; Xiong, L.-X.; Li, Z.-M. Synthesis, Structure and Insecticidal Activities of Some Novel Amides Containing N-Pyridylpyrazole Moeities. Molecules 2012, 17, 10414-10428.

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