Molecules 2012, 17(9), 10414-10428; doi:10.3390/molecules170910414
Article

Synthesis, Structure and Insecticidal Activities of Some Novel Amides Containing N-Pyridylpyrazole Moeities

1 Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, Tianjin 300070, China 2 State Key Laboratory of Elemento-Organic Chemistry, National Pesticide Engineering Research Center, Nankai University, Tianjin 300071, China
* Author to whom correspondence should be addressed.
Received: 1 August 2012; in revised form: 13 August 2012 / Accepted: 18 August 2012 / Published: 31 August 2012
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Abstract: In our search for environmentally benign insecticides with high activity, low toxicity and low residue, a novel series of amides containing N-pyridylpyrazole moieties were designed and synthesized. The structures of the title compounds were characterized and confirmed by 1H-NMR and elemental analysis. Furthermore, the structure of compound 7l was determined by single crystal X-ray diffraction. The preliminary bioassay tests showed that some of them exhibited good insecticidal activities against Mythimna separata Walker, Plutella xylostella (Linnaeus, 1758) and Laphygma exigua Hübner.
Keywords: amide; N-pyridylpyrazole; synthesis; crystal structure; insecticidal activity

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MDPI and ACS Style

Dong, W.-L.; Xu, J.-Y.; Xiong, L.-X.; Li, Z.-M. Synthesis, Structure and Insecticidal Activities of Some Novel Amides Containing N-Pyridylpyrazole Moeities. Molecules 2012, 17, 10414-10428.

AMA Style

Dong W-L, Xu J-Y, Xiong L-X, Li Z-M. Synthesis, Structure and Insecticidal Activities of Some Novel Amides Containing N-Pyridylpyrazole Moeities. Molecules. 2012; 17(9):10414-10428.

Chicago/Turabian Style

Dong, Wei-Li; Xu, Jing-Ying; Xiong, Li-Xia; Li, Zheng-Ming. 2012. "Synthesis, Structure and Insecticidal Activities of Some Novel Amides Containing N-Pyridylpyrazole Moeities." Molecules 17, no. 9: 10414-10428.

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