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Molecules 2012, 17(9), 10072-10078; doi:10.3390/molecules170910072

A New Cubitane Diterpenoid from the Soft Coral Sinularia crassa

1 Department of Neurosurgery, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Kaohsiung 833, Taiwan 2 Department of Biological Science and Technology, Meiho University, Pingtung 912, Taiwan 3 Department of Marine Biotechnology and Resources and Asia-Pacific Ocean Research Center, National Sun Yat-sen University, Kaohsiung 833, Taiwan 4 National Museum of Marine Biology & Aquarium, Pingtung 944, Taiwan 5 Graduate Institute of Marine Biotechnology, National Dong Hwa University, Pingtung 944, Taiwan
* Author to whom correspondence should be addressed.
Received: 12 July 2012 / Revised: 10 August 2012 / Accepted: 15 August 2012 / Published: 24 August 2012
(This article belongs to the Section Natural Products)
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A new cubitane diterpenoid, crassalone A (1), was isolated from the marine soft coral Sinularia crassa. The structure was determined by extensive spectroscopic analyses. Compound 1 is not cytotoxic (IC50 > 20 μg/mL) toward the four human cancer cell lines tested (HL60, MDA-MB-231, HCT-116 and DLD-1).
Keywords: diterpenes; soft coral; Sinularia crassa diterpenes; soft coral; Sinularia crassa
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Cheng, C.-H.; Lin, Y.-S.; Wen, Z.-H.; Su, J.-H. A New Cubitane Diterpenoid from the Soft Coral Sinularia crassa. Molecules 2012, 17, 10072-10078.

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