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A New Cubitane Diterpenoid from the Soft Coral Sinularia crassa
Department of Neurosurgery, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Kaohsiung 833, Taiwan
Department of Biological Science and Technology, Meiho University, Pingtung 912, Taiwan
Department of Marine Biotechnology and Resources and Asia-Pacific Ocean Research Center, National Sun Yat-sen University, Kaohsiung 833, Taiwan
National Museum of Marine Biology & Aquarium, Pingtung 944, Taiwan
Graduate Institute of Marine Biotechnology, National Dong Hwa University, Pingtung 944, Taiwan
* Author to whom correspondence should be addressed.
Received: 12 July 2012; in revised form: 10 August 2012 / Accepted: 15 August 2012 / Published: 24 August 2012
Abstract: A new cubitane diterpenoid, crassalone A (1), was isolated from the marine soft coral Sinularia crassa. The structure was determined by extensive spectroscopic analyses. Compound 1 is not cytotoxic (IC50 > 20 μg/mL) toward the four human cancer cell lines tested (HL60, MDA-MB-231, HCT-116 and DLD-1).
Keywords: diterpenes; soft coral; Sinularia crassa
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MDPI and ACS Style
Cheng, C.-H.; Lin, Y.-S.; Wen, Z.-H.; Su, J.-H. A New Cubitane Diterpenoid from the Soft Coral Sinularia crassa. Molecules 2012, 17, 10072-10078.
Cheng C-H, Lin Y-S, Wen Z-H, Su J-H. A New Cubitane Diterpenoid from the Soft Coral Sinularia crassa. Molecules. 2012; 17(9):10072-10078.
Cheng, Ching-Hsiao; Lin, Yun-Sheng; Wen, Zhi-Hong; Su, Jui-Hsin. 2012. "A New Cubitane Diterpenoid from the Soft Coral Sinularia crassa." Molecules 17, no. 9: 10072-10078.