Next Article in Journal
Isolation of Glycinin (11S) from Lipid-Reduced Soybean Flour: Effect of Processing Conditions on Yields and Purity
Previous Article in Journal
α-Mangostin Enhances Betulinic Acid Cytotoxicity and Inhibits Cisplatin Cytotoxicity on HCT 116 Colorectal Carcinoma Cells
Article Menu

Article Versions

Export Article

Open AccessArticle
Molecules 2012, 17(3), 2955-2967; doi:10.3390/molecules17032955

Evaluation of Traditional Chinese Medicinal Plants for Anti-MRSA Activity with Reference to the Treatment Record of Infectious Diseases

1
Research Center for Natural Medicines, Kunming General Hospital, PLA, Kunming 650032, China
2
Kunming Medical College, Kunming 650032, China
3
Yunnan Traditional Chinese Medical College, Kunming 650500, China
4
Center for Infectious Diseases, Kunming General Hospital, PLA, Kunming 650032, China
These authors contributed equally to this work.
*
Authors to whom correspondence should be addressed.
Received: 8 February 2012 / Revised: 27 February 2012 / Accepted: 29 February 2012 / Published: 9 March 2012
Download PDF [211 KB, uploaded 18 June 2014]

Abstract

The in vitro antimicrobial activities of 30 Chinese medicinal plants were evaluated with reference to the treatment record of infectious diseases in the Traditional Chinese Medicine (TCM) literature. The plant materials were extracted with 80% ethanol and the extracts were primarily screened against conventional clinical pathogens like Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Candida albicans by the agar diffusion method. Their inhibition zone diameters (IZDs, mm, 50 mg/mL) ranged from 2,048 by the standard broth microdilution method. The seven extracts from M. yunnanensis, S. sinensis, G. morella, E. daneillii, M. squamulata, S. arborescens and B. hancei were determined as the most active extracts, with MICs of 8–64 μg/mL. The results were in good agreement with their traditional applications in skin and other infections.
Keywords: Chinese medicinal plants; traditional Chinese medicine (TCM); methicillin-resistant Staphylococcus aureus (MRSA); inhibition zone diameters (IZD); minimal bactericidal concentrations (MIC) Chinese medicinal plants; traditional Chinese medicine (TCM); methicillin-resistant Staphylococcus aureus (MRSA); inhibition zone diameters (IZD); minimal bactericidal concentrations (MIC)
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Zuo, G.-Y.; Zhang, X.-J.; Yang, C.-X.; Han, J.; Wang, G.-C.; Bian, Z.-Q. Evaluation of Traditional Chinese Medicinal Plants for Anti-MRSA Activity with Reference to the Treatment Record of Infectious Diseases. Molecules 2012, 17, 2955-2967.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top