Next Article in Journal
Convergent Synthesis of the Potent P2Y Receptor Antagonist MG 50-3-1 Based on a Regioselective Ullmann Coupling Reaction
Previous Article in Journal
Anti-Addition Mechanism in the Intramolecular Hydroalkoxylation of Alkenes Catalyzed by PVP-Stabilized Nanogold
Article Menu

Article Versions

Export Article

Open AccessArticle
Molecules 2012, 17(3), 2587-2598; doi:10.3390/molecules17032587

New Constituents from the Rhizomes of Egyptian Iris germanica L.

1
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt
2
Department of Natural products, Faculty of Pharmacy, King Abdulaziz University, Jeddah 211589, Saudi Arabia
3
Department of Pharmacognosy, Faculty of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia
Permanent address: Department of Pharmacognosy, Faculty of Pharmacy, Al-Azhar University, Assiut Branch, Assiut 71524, Egypt
*
Author to whom correspondence should be addressed.
Received: 5 February 2012 / Revised: 23 February 2012 / Accepted: 28 February 2012 / Published: 2 March 2012
(This article belongs to the Section Natural Products)
Download PDF [354 KB, 18 June 2014; original version 18 June 2014]

Abstract

Chemical investigation of the methanolic extract of the rhizomes of Iris germanica L. (Iridaceae) afforded two new compounds; irigenin S (7) and iriside A (12), together with ten known compounds: stigmasterol (1), a-irone (2), γ-irone (3), 3-hydroxy-5-methoxyacetophenone (4), irilone (5), irisolidone (6), irigenin (8), stigmasterol-3-O-β-D-glucopyranoside (9), irilone 4'-O-b-D-glucopyranoside (10) and iridin (11). Their structures were established by UV, IR, 1D (1H and 13C) and 2D (1H-1H COSY, HMQC, and HMBC) NMR spectroscopy, in addition to mass spectroscopic data and comparison with literature data. The methanolic extract was evaluated for its antimicrobial activity. Both the methanolic extract and the isolated flavonoids were tested for their anti-inflammatory activity.
Keywords: Iris germanica L.; Iridaceae; irigenin S; iriside A; antimicrobial; anti-inflammatory Iris germanica L.; Iridaceae; irigenin S; iriside A; antimicrobial; anti-inflammatory
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Ibrahim, S.R.M.; Mohamed, G.A.; Al-Musayeib, N.M. New Constituents from the Rhizomes of Egyptian Iris germanica L.. Molecules 2012, 17, 2587-2598.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top