New Furanones from the Plant Endophytic Fungus Pestalotiopsis besseyi
Abstract
:1. Introduction
2. Results and Discussion
2.1. Structural Elucidation
Position | 1 a | 2 a | 3 a | 4 a | 5 a |
---|---|---|---|---|---|
5 | 4.65, s | 4.85, s | 4.63, s | 4.78, s | 4.78, d (17) |
4.71, d (17) | |||||
6 | 6.10, d (16) | 6.26, d (16) | 2.45, t (7.5) | 6.24, d (16) | 2.61, t (7.5) |
7 | 6.86, m | 6.97, m | 1.52, m | 6.85, m | 1.55, m |
8 | 1.86, d (7.0) | 1.89, d (6.7) | 0.93, t (7.5) | 1.81, d (6.5) | 0.94, t (7.5) |
9 | 2.70, m | 6.77, d (16) | 2.67, br s | 2.90, dd (15, 3.6) | 2.86, dd (12, 4.0) |
2.65, dd (15, 6.0) | 2.44, dd (12, 7.0) | ||||
10 | 2.70, m | 6.04, dd (16, 7.7) | 2.67, br s | 2.77, m | 2.75, ddd (7.0, 4.0, 2.0) |
11 | 4.52, m | 2.85, dq (4.5, 2.0) | 2.81, dq (7.5, 2.0) | ||
11-OH | 1.75, br s | ||||
12 | 2.18, s | 1.68, d (7.0) | 2.19, s | 1.24, d (4.5) | 0.93, d (7.5) |
Position | 1 a | 2 a | 3 a | 4 a | 5 a | ||||
---|---|---|---|---|---|---|---|---|---|
2 | 172.9, qC | 173.0, qC | 177.5, qC | 173.0, qC | 174.5, qC | ||||
3 | 123.3, qC | 122.7, qC | 127.9, qC | 123.9, qC | 128.7, qC | ||||
4 | 156.6, qC | 149.4, qC | 158.9, qC | 156.3, qC | 158.5, qC | ||||
5 | 70.8, CH2 | 68.6, CH2 | 71.2, CH2 | 71.7, CH2 | 71.8, CH2 | ||||
6 | 118.1, CH | 118.7, CH | 25.6 CH2 | 119.9, CH | 25.6, CH2 | ||||
7 | 133.0, CH | 134.3, CH | 20.6 CH2 | 132.3, CH | 21.4, CH2 | ||||
8 | 19.3, CH3 | 19.6, CH3 | 13.9, CH3 | 17.4, CH3 | 13.9, CH3 | ||||
9 | 20.4, CH2 | 118.6, CH | 21.3, CH2 | 30.2, CH2 | 29.9 CH2 | ||||
10 | 41.0, CH2 | 140.8, CH | 41.3, CH2 | 57.2, CH | 56.8, CH | ||||
11 | 206.1, qC | 68.3, CH | 206.0, qC | 54.7, CH | 54.5, CH | ||||
12 | 29.8, CH3 | 23.5, CH3 | 29.8, CH3 | 19.1, CH3 | 17.2, CH3 |
2.2. Anti-HIV Activity
2.3. Antifungal Activity
3. Experimental
3.1. General
3.2. Fungal Material
3.3. Extraction and Isolation
3.4. Anti-HIV Assay
3.5. Antifungal Bioassay
4. Conclusions
Acknowledgments
References
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© 2012 by the authors; licensee MDPI, Basel, Switzerland. This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
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Liu, H.; Liu, S.; Guo, L.; Zhang, Y.; Cui, L.; Ding, G. New Furanones from the Plant Endophytic Fungus Pestalotiopsis besseyi. Molecules 2012, 17, 14015-14021. https://doi.org/10.3390/molecules171214015
Liu H, Liu S, Guo L, Zhang Y, Cui L, Ding G. New Furanones from the Plant Endophytic Fungus Pestalotiopsis besseyi. Molecules. 2012; 17(12):14015-14021. https://doi.org/10.3390/molecules171214015
Chicago/Turabian StyleLiu, Haitao, Shuchun Liu, Liangdong Guo, Yonggang Zhang, Langjun Cui, and Gang Ding. 2012. "New Furanones from the Plant Endophytic Fungus Pestalotiopsis besseyi" Molecules 17, no. 12: 14015-14021. https://doi.org/10.3390/molecules171214015