Isolation and Identification of the Phenolic Compounds from the Roots of Sanguisorba officinalis L. and Their Antioxidant Activities
Abstract
:1. Introduction
2. Results and Discussion
2.1. Isolation and Identification of Compounds 1–4
No. | δC | δH | HMBC (H→C) | No. | δC | δH | HMBC (H→C) |
---|---|---|---|---|---|---|---|
aglycone | glc | ||||||
1 | 125.0 | 1ʹ | 104.5 | 4.83 (d, 1H, J = 6.0 Hz) | 138.8 | ||
2 | 102.9 | 6.92 (s, 1H) | 111.8, 138.8, 166.2 | 2ʹ | 74.0 | 3.27 (m, 1H) | |
3 | 153.0 | 3ʹ | 76.5 | 3.22 (m, 1H) | |||
4 | 138.8 | 4ʹ | 69.6 | 3.20 (m, 1H) | |||
5 | 152.6 | 5ʹ | 77.3 | 3.13 (m, 1H) | |||
6 | 111.8 | 7.03 (s, 1H) | 102.9, 138.8, 166.2 | 6ʹ | 60.7 | 3.49 (m, 1H), 3.62 (d-like, 1H, J = 10.4 Hz) | |
7 | 166.2 | ||||||
3-OCH3 | 56.2 | 3.77 | 153.0 | ||||
7-OCH3 | 51.9 | 3.79 | 166.2 |
2.2. Antioxidant Activity of Compounds 1–4
Compound | IC50 (ug/mL) |
---|---|
Methyl 4-O-β-D-glucopyranosy-5-hydroxy-3-methoxylbenzoate (1) | 720 ± 7.3 |
3,3′,4′-tri-O-Methylellagic acid (2) | 820 ± 7.3 |
Fisetinidol-(4α-8)-catechin (3) | 12.3 ± 0.2 |
(+)-Catechin (4) | 38.2 ± 0.5 |
3. Experimental
3.1. General
3.2. Extraction and Isolation
3.3. Acid Hydrolysis of 1
3.4. Bioactivity Assay
4. Conclusions
Acknowledgments
References
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Zhang, S.; Liu, X.; Zhang, Z.-L.; He, L.; Wang, Z.; Wang, G.-S. Isolation and Identification of the Phenolic Compounds from the Roots of Sanguisorba officinalis L. and Their Antioxidant Activities. Molecules 2012, 17, 13917-13922. https://doi.org/10.3390/molecules171213917
Zhang S, Liu X, Zhang Z-L, He L, Wang Z, Wang G-S. Isolation and Identification of the Phenolic Compounds from the Roots of Sanguisorba officinalis L. and Their Antioxidant Activities. Molecules. 2012; 17(12):13917-13922. https://doi.org/10.3390/molecules171213917
Chicago/Turabian StyleZhang, Shuang, Xin Liu, Zi-Long Zhang, Lu He, Zhe Wang, and Guang-Shu Wang. 2012. "Isolation and Identification of the Phenolic Compounds from the Roots of Sanguisorba officinalis L. and Their Antioxidant Activities" Molecules 17, no. 12: 13917-13922. https://doi.org/10.3390/molecules171213917