Isolation and Identification of the Phenolic Compounds from the Roots of Sanguisorba officinalis L. and Their Antioxidant Activities

doi:10.3390/molecules171213917

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Molecules 2012, 17(12), 13917-13922; doi:10.3390/molecules171213917

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Isolation and Identification of the Phenolic Compounds from the Roots of Sanguisorba officinalis L. and Their Antioxidant Activities

Shuang Zhang, Xin Liu, Zi-Long Zhang, Lu He, Zhe Wang and Guang-Shu Wang*

School of Pharmaceutical Sciences, Jilin University, Changchun 130021, China

* Author to whom correspondence should be addressed.

Received: 26 September 2012; in revised form: 15 November 2012 / Accepted: 16 November 2012 / Published: 23 November 2012

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Abstract: Four phenolic compounds were isolated from the roots of Sanguisorba officinalis L. by silica gel column chromatography and preparative HPLC. On the basis of chemical and spectroscopic methods, their structures were identified as methyl 4-O-β-D-glucopyranosy-5-hydroxy-3-methoxylbenzoate (1), 3,3′,4′-tri-O-methylellagic acid (2), fisetinidol-(4α-8)-catechin (3), and (+)-catechin (4). Compound 1 is a new phenolic glycoside and compounds 2 and 3 were isolated from the Sanguisorba genus for the first time. Compounds 1–4 were also assayed for their antioxidant activities using the DPPH free radical assay.

Keywords: Sanguisorba officinalis; isolation; antioxidant activities; phenolic glycoside; fisetinidol-(4α-8)-catechin; ellagic acid; catechin

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Cite This Article

MDPI and ACS Style

Zhang, S.; Liu, X.; Zhang, Z.-L.; He, L.; Wang, Z.; Wang, G.-S. Isolation and Identification of the Phenolic Compounds from the Roots of Sanguisorba officinalis L. and Their Antioxidant Activities. Molecules 2012, 17, 13917-13922.

AMA Style

Zhang S, Liu X, Zhang Z-L, He L, Wang Z, Wang G-S. Isolation and Identification of the Phenolic Compounds from the Roots of Sanguisorba officinalis L. and Their Antioxidant Activities. Molecules. 2012; 17(12):13917-13922.

Chicago/Turabian Style

Zhang, Shuang; Liu, Xin; Zhang, Zi-Long; He, Lu; Wang, Zhe; Wang, Guang-Shu. 2012. "Isolation and Identification of the Phenolic Compounds from the Roots of Sanguisorba officinalis L. and Their Antioxidant Activities." Molecules 17, no. 12: 13917-13922.

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