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Molecules 2012, 17(12), 13787-13794; doi:10.3390/molecules171213787

Spiroheterocyclization of Methyl 1-Aryl-3-cinnamoyl-4,5-dioxo-4,5-dihydro-1H-pyrrole-2-carboxylates by the Action of 3-(Arylamino)-1H-inden-1-ones

1 Department of Organic Chemistry, Perm State National Research University, Perm 614066, Russia 2 Ya. Postovskiy Institute of Organic Synthesis, Russian Academy of Science, Ural Branch, Yekaterinburg 620219, Russia
* Author to whom correspondence should be addressed.
Received: 19 October 2012 / Revised: 2 November 2012 / Accepted: 5 November 2012 / Published: 22 November 2012
(This article belongs to the Special Issue Spiro Compounds)
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Methyl 1-aryl-3-cinnamoyl-4,5-dioxo-4,5-dihydro-1H-pyrrole-2-carboxylates interact with 3-(arylamino)-1H-inden-1-ones to give the corresponding 1,1'-diaryl-3'-cinnamoyl-4'-hydroxy-1H-spiro[indeno[1,2-b]pyrrole-3,2'-pyrrole]-2,4,5'(1'H)-triones in good yields.
Keywords: pyrrole-2,3-diones; enamines; spiro[indeno[1,2-b]pyrrole-3,2'-pyrroles] pyrrole-2,3-diones; enamines; spiro[indeno[1,2-b]pyrrole-3,2'-pyrroles]
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Silaichev, P.S.; Filimonov, V.O.; Slepukhin, P.A.; Maslivets, А.N. Spiroheterocyclization of Methyl 1-Aryl-3-cinnamoyl-4,5-dioxo-4,5-dihydro-1H-pyrrole-2-carboxylates by the Action of 3-(Arylamino)-1H-inden-1-ones. Molecules 2012, 17, 13787-13794.

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