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Molecules 2012, 17(10), 12121-12139; doi:10.3390/molecules171012121
Article

Suzuki-Miyaura Reactions Catalyzed by C2-Symmetric Pd-Multi-Dentate N-Heterocyclic Carbene Complexes

1,2
, 2
, 2,*  and 1,*
1 State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian 116024, China 2 College of Environmental and Chemical Engineering, Dalian University, Dalian 116622, China
* Authors to whom correspondence should be addressed.
Received: 20 September 2012 / Revised: 6 October 2012 / Accepted: 9 October 2012 / Published: 16 October 2012
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Abstract

Suzuki-Miyaura coupling reactions are promoted by Pd complexes ligated with C2-symmetric multi-dentate N-heterocyclic carbenes derived in situ from Pd(OAc)2 and imidazolium salts. Good to excellent yields were obtained for aryl bromides as substrates. Turnover numbers of up to 105 could be achieved with 5 × 10−4 mol% of Pd(OAc)2/1 × 10−3 mol% NHC precatalyst in 24 h.
Keywords: imidazolium salt; N-heterocyclic carbene; palladium; Suzuki-Miyaura coupling; catalysis imidazolium salt; N-heterocyclic carbene; palladium; Suzuki-Miyaura coupling; catalysis
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Jiang, L.; Shan, F.; Li, Z.; Zhao, D. Suzuki-Miyaura Reactions Catalyzed by C2-Symmetric Pd-Multi-Dentate N-Heterocyclic Carbene Complexes. Molecules 2012, 17, 12121-12139.

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