Next Article in Journal
Previous Article in Journal
Molecules 2011, 16(5), 4059-4069; doi:10.3390/molecules16054059
Article

Synthesis of Ginkgolic Acid Analogues and Evaluation of Their Molluscicidal Activity

1, 1, 2, 2, 1, 3, 3, 2,*  and 1,*
Received: 16 March 2011; in revised form: 23 April 2011 / Accepted: 9 May 2011 / Published: 17 May 2011
Download PDF [196 KB, uploaded 18 June 2014]
Abstract: Based on the molluscicidal activity of ginkgolic acids (GAs) isolated from Ginkgo biloba L, a series of Z/E isomers of GA analogues were prepared and evaluated for their molluscicidal activities against the host snail Oncomelania hupensis. The results and analysis of the structure-activity relationship revealed that the E-isomers showed better molluscicidal activities than their Z-isomers. Molluscicidal activities decreased with the shortening of the alkenyl chain lengths.
Keywords: ginkgolic acid analogues; synthesis; molluscicidal activity; snail; schistosomiasis ginkgolic acid analogues; synthesis; molluscicidal activity; snail; schistosomiasis
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Export to BibTeX |
EndNote


MDPI and ACS Style

Zhang, P.; Pan, J.; Duan, W.; Li, X.; Zhang, Y.; Zhou, Y.; Jiang, Q.; Mao, Z.; Yu, P. Synthesis of Ginkgolic Acid Analogues and Evaluation of Their Molluscicidal Activity. Molecules 2011, 16, 4059-4069.

AMA Style

Zhang P, Pan J, Duan W, Li X, Zhang Y, Zhou Y, Jiang Q, Mao Z, Yu P. Synthesis of Ginkgolic Acid Analogues and Evaluation of Their Molluscicidal Activity. Molecules. 2011; 16(5):4059-4069.

Chicago/Turabian Style

Zhang, Peng; Pan, Jiahu; Duan, Wanxing; Li, Xuedong; Zhang, Yao; Zhou, Yibiao; Jiang, Qingwu; Mao, Zuohua; Yu, Peizhong. 2011. "Synthesis of Ginkgolic Acid Analogues and Evaluation of Their Molluscicidal Activity." Molecules 16, no. 5: 4059-4069.



Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert