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Molecules 2011, 16(3), 2609-2625; doi:10.3390/molecules16032609

Chemical Composition and In Vitro Activity of Plant Extracts from Ferula communis and Dittrichia viscosa against Postharvest Fungi

1,2, 2,* , 2, 3, 2 and 4
1 Dipartimento di Science per l'Ambiente, Università degli Studi di Napoli "Parthenope" Centro Direzionale, Isola C4, 80143 Napoli, Italy 2 Istituto Agronomico Mediterraneo di Bari,Via Ceglie 9, 70010 Valenzano, Italy 3 Dipartimento di Biologia e Chimica Agro-Forestale ed Ambientale, Università degli Studi di Bari, Via Amendola 165/A, 70126 Bari, Italy 4 Dipartimento di Tossicologia, Università degli Studi di Cagliari, Via Ospedale 72, 09124 Cagliari, Italy
* Author to whom correspondence should be addressed.
Received: 1 March 2011 / Revised: 15 March 2011 / Accepted: 18 March 2011 / Published: 22 March 2011
(This article belongs to the Section Natural Products)
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F. communis and D. viscosa are perennial Mediterranean weeds that have been used for different therapeutic purposes in traditional pharmacopeia. Plant extracts were obtained from air dried D. viscosa young shoots (DvA) and F. communis aerial part (FcA) and roots (FcR) with n-hexane. The chemical compositions of the extracts were analyzed by HPLC-DAD, LC-MS (ESI) and LC-Q-TOF techniques. Two sesquiterpene lactones (inuviscolide, tomentosin) and three sesquiterpene acids (costic acid, hydroxycostic acid, ilicic acid) were identified from the D. viscosa extract, while in F. communis extracts three daucane sesquiterpenes (acetoxyferutinin, oxojaeskeanadioyl anisate, fertidin) and one coumarin (ferulenol) derivates were found. Biological activities of plant extracts were studied in in vitro experiments on the colonies and conidia of Botryotinia fuckeliana, Penicillium digitatum, P. expansum, Monilinia laxa, M. fructigena and Aspergillus spp. Extracts showed varying degree of antifungal activities on colony growth and conidia germination. The extract from FcA showed the least effect, while DvA extract had the strongest fungitoxic effects. FcR extract presented a fungitoxic effect on the colony growth, but it was not able to inhibit the conidia germination. These distinctions can be attributed to the differences in chemical composition of plant extracts.
Keywords: plant extracts; sesquiterpenes; coumarin; postharvest fungi plant extracts; sesquiterpenes; coumarin; postharvest fungi
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Mamoci, E.; Cavoski, I.; Simeone, V.; Mondelli, D.; Al-Bitar, L.; Caboni, P. Chemical Composition and In Vitro Activity of Plant Extracts from Ferula communis and Dittrichia viscosa against Postharvest Fungi. Molecules 2011, 16, 2609-2625.

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