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Molecules 2010, 15(5), 3171-3178; doi:10.3390/molecules15053171
Article

Convenient and Efficient Microwave-Assisted Synthesis of a Methyl Derivative of the Fused Indoloquinoline Alkaloid Cryptosanguinolentine

1,* , 1,2,* , 2 and 2
Received: 10 March 2010 / Revised: 2 April 2010 / Accepted: 7 April 2010 / Published: 29 April 2010
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Abstract

An efficient synthesis of a methyl derivative of the indoloquinoline alkaloid cryptosanguinolentine based on microwave-assisted reactions is described. The microwave-assisted synthesis of an intermediate 4-hydroxy-2-methylquinoline yielded 86% of the desired product and other intermediates prepared yielded high % of products in shorter reaction times, under optimum conditions, as compared to traditional methods.
Keywords: cryptosanguinolentine; microwave; phase transfer catalysis cryptosanguinolentine; microwave; phase transfer catalysis
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Gengan, R.M.; Pandian, P.; Kumarsamy, C.; Mohan, P.S. Convenient and Efficient Microwave-Assisted Synthesis of a Methyl Derivative of the Fused Indoloquinoline Alkaloid Cryptosanguinolentine. Molecules 2010, 15, 3171-3178.

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