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Molecules 2010, 15(5), 3171-3178; doi:10.3390/molecules15053171

Convenient and Efficient Microwave-Assisted Synthesis of a Methyl Derivative of the Fused Indoloquinoline Alkaloid Cryptosanguinolentine

Department of Chemistry, Steve Biko Campus, Durban University of Technology, Durban-4001, South Africa
Department of Chemistry, School of Chemical Sciences, Bharathiar University, Coimbatore-641046, Tamil Nadu, India
Authors to whom correspondence should be addressed.
Received: 10 March 2010 / Revised: 2 April 2010 / Accepted: 7 April 2010 / Published: 29 April 2010
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An efficient synthesis of a methyl derivative of the indoloquinoline alkaloid cryptosanguinolentine based on microwave-assisted reactions is described. The microwave-assisted synthesis of an intermediate 4-hydroxy-2-methylquinoline yielded 86% of the desired product and other intermediates prepared yielded high % of products in shorter reaction times, under optimum conditions, as compared to traditional methods.
Keywords: cryptosanguinolentine; microwave; phase transfer catalysis cryptosanguinolentine; microwave; phase transfer catalysis

This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Gengan, R.M.; Pandian, P.; Kumarsamy, C.; Mohan, P.S. Convenient and Efficient Microwave-Assisted Synthesis of a Methyl Derivative of the Fused Indoloquinoline Alkaloid Cryptosanguinolentine. Molecules 2010, 15, 3171-3178.

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