Molecules 2010, 15(4), 2087-2095; doi:10.3390/molecules15042087
Article

Ultrasound-Assisted Synthesis of Novel 4-(2-Phenyl-1,2,3-Triazol-4-yl)-3,4-Dihydropyrimidin-2(1H)-(Thio)ones Catalyzed by Sm(ClO4)3

1,2email and 1,2,* email
1 School of Science, Xi\'an Jiaotong University, 710049 Xi\'an, China 2 School of Chemistry and Chemical Engineering, Xinjiang University, Key Laboratory of Oil and Gas Fine Chemicals, Ministry of Education, 830046 Urumqi, China
* Author to whom correspondence should be addressed.
Received: 28 January 2010; in revised form: 15 March 2010 / Accepted: 24 March 2010 / Published: 24 March 2010
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Abstract: An efficient synthesis of novel 4-(2-phenyl-1,2,3-triazol-4-yl)-3,4-dihydro-pyrimidin-2(1H)-(thio)ones from 1,3-dicarbonyl compounds, 2-phenyl-1,2,3-triazole-4-carbaldehyde and urea or thiourea under ultrasound irradiation and using samarium perchlorate as catalyst is described. Compared with conventional methods, the main advantages of the present methodology are milder conditions, shorter reaction times and higher yields.
Keywords: Biginelli reaction; dihydropyrimidinone; triazole; Sm(ClO4)3; ultrasound

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MDPI and ACS Style

Liu, C.-J.; Wang, J.-D. Ultrasound-Assisted Synthesis of Novel 4-(2-Phenyl-1,2,3-Triazol-4-yl)-3,4-Dihydropyrimidin-2(1H)-(Thio)ones Catalyzed by Sm(ClO4)3. Molecules 2010, 15, 2087-2095.

AMA Style

Liu C-J, Wang J-D. Ultrasound-Assisted Synthesis of Novel 4-(2-Phenyl-1,2,3-Triazol-4-yl)-3,4-Dihydropyrimidin-2(1H)-(Thio)ones Catalyzed by Sm(ClO4)3. Molecules. 2010; 15(4):2087-2095.

Chicago/Turabian Style

Liu, Chen-Jiang; Wang, Ji-De. 2010. "Ultrasound-Assisted Synthesis of Novel 4-(2-Phenyl-1,2,3-Triazol-4-yl)-3,4-Dihydropyrimidin-2(1H)-(Thio)ones Catalyzed by Sm(ClO4)3." Molecules 15, no. 4: 2087-2095.

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