Next Article in Journal
Triterpenes from Stachyurus himalaicus var. himalaicus Hook. f. et Thoms. ex Benth
Previous Article in Journal
Inhibitory Effect of Ginkgo Biloba Extract on the Tonus of the Small Intestine and the Colon of Rabbits
Article Menu

Article Versions

Export Article

Open AccessArticle
Molecules 2010, 15(4), 2087-2095; doi:10.3390/molecules15042087

Ultrasound-Assisted Synthesis of Novel 4-(2-Phenyl-1,2,3-Triazol-4-yl)-3,4-Dihydropyrimidin-2(1H)-(Thio)ones Catalyzed by Sm(ClO4)3

1
School of Science, Xi'an Jiaotong University, 710049 Xi'an, China
2
School of Chemistry and Chemical Engineering, Xinjiang University, Key Laboratory of Oil and Gas Fine Chemicals, Ministry of Education, 830046 Urumqi, China
*
Author to whom correspondence should be addressed.
Received: 28 January 2010 / Revised: 15 March 2010 / Accepted: 24 March 2010 / Published: 24 March 2010
Download PDF [150 KB, uploaded 18 June 2014]

Abstract

An efficient synthesis of novel 4-(2-phenyl-1,2,3-triazol-4-yl)-3,4-dihydro-pyrimidin-2(1H)-(thio)ones from 1,3-dicarbonyl compounds, 2-phenyl-1,2,3-triazole-4-carbaldehyde and urea or thiourea under ultrasound irradiation and using samarium perchlorate as catalyst is described. Compared with conventional methods, the main advantages of the present methodology are milder conditions, shorter reaction times and higher yields.
Keywords: Biginelli reaction; dihydropyrimidinone; triazole; Sm(ClO4)3; ultrasound Biginelli reaction; dihydropyrimidinone; triazole; Sm(ClO4)3; ultrasound
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Liu, C.-J.; Wang, J.-D. Ultrasound-Assisted Synthesis of Novel 4-(2-Phenyl-1,2,3-Triazol-4-yl)-3,4-Dihydropyrimidin-2(1H)-(Thio)ones Catalyzed by Sm(ClO4)3. Molecules 2010, 15, 2087-2095.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top