Molecules 2009, 14(9), 3694-3699; doi:10.3390/molecules14093694
Article

A New Cytotoxic 19-Nor-cardenolide from the Latex of Antiaris toxicaria

Hao-Fu Dai 1 email, Yu-Juan Gan 1 email, Dong-Mei Que 1 email, Jiao Wu 1 email, Zhen-Chang Wen 2 email and Wen-Li Mei 1,* email
1 Key Laboratory of Tropical Crop Biotechnology, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China 2 Key Laboratory of Tropic Biological Resources of Ministry of Education, Hainan University, Haikou 570228, China
* Author to whom correspondence should be addressed.
Received: 22 July 2009; in revised form: 8 September 2009 / Accepted: 15 September 2009 / Published: 21 September 2009
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Abstract: A new nor-cardenolide, named toxicarioside H (1), was isolated from the latex of Antiaris toxicaria (Pers.) Lesch (Moraceae). Its structure was elucidated on the basis of HRFAB-MS and spectroscopic techniques (IR, UV, 1D and 2D NMR). Compound 1 showed significant cytotoxicity against K562, SGC-7901, SMMC-7721, and HeLa cell lines in vitro by MTT method.
Keywords: Antiaris toxicaria; toxicarioside H; nor-cardenolide; cytotoxicity

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Cite This Article

MDPI and ACS Style

Dai, H.-F.; Gan, Y.-J.; Que, D.-M.; Wu, J.; Wen, Z.-C.; Mei, W.-L. A New Cytotoxic 19-Nor-cardenolide from the Latex of Antiaris toxicaria. Molecules 2009, 14, 3694-3699.

AMA Style

Dai H-F, Gan Y-J, Que D-M, Wu J, Wen Z-C, Mei W-L. A New Cytotoxic 19-Nor-cardenolide from the Latex of Antiaris toxicaria. Molecules. 2009; 14(9):3694-3699.

Chicago/Turabian Style

Dai, Hao-Fu; Gan, Yu-Juan; Que, Dong-Mei; Wu, Jiao; Wen, Zhen-Chang; Mei, Wen-Li. 2009. "A New Cytotoxic 19-Nor-cardenolide from the Latex of Antiaris toxicaria." Molecules 14, no. 9: 3694-3699.

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