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Molecules 2009, 14(9), 3222-3228; doi:10.3390/molecules14093222

Conjugate Addition of Indoles to α,β-Unsaturated Ketones Using a Brønsted Acid Ionic Liquid as an Efficient Catalyst

School of Chemistry and Chemical Engineering, Xinjiang University, Key Laboratory of Oil and Gas Fine Chemicals, Ministry of Education, 830046 Urumqi, China
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Received: 6 July 2009 / Revised: 20 August 2009 / Accepted: 24 August 2009 / Published: 27 August 2009
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Abstract

The Brønsted acid ionic liquid [PyN(CH2)4SO3H][p-CH3PhSO3] has been reported as an efficient catalyst for the Michael addition reaction of indoles to α,β-unsaturated ketones. Satisfactory results were obtained, with excellent yields and a simple experimental procedure. The catalyst could be recycled and reused up to three times without any noticeable decrease in the catalytic activity.
Keywords: Brønsted acid ionic liquid; β-indolylketones; Michael addition Brønsted acid ionic liquid; β-indolylketones; Michael addition
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Yu, C.-J.; Liu, C.-J. Conjugate Addition of Indoles to α,β-Unsaturated Ketones Using a Brønsted Acid Ionic Liquid as an Efficient Catalyst. Molecules 2009, 14, 3222-3228.

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