Next Article in Journal
The Effect of Dye Density on the Efficiency of Photosensitization of TiO2 Films: Light-Harvesting by Phenothiazine-Labelled Dendritic Ruthenium Complexes
Previous Article in Journal
Amides from Piper capense with CNS Activity – A Preliminary SAR Analysis
Molecules 2009, 14(10), 3844-3850; doi:10.3390/molecules14103844
Article

Ugandenial A, a New Drimane-type Sesquiterpenoid from Warburgia ugandensis

1
,
2,* , 3
,
2
,
4
,
5
,
2
 and
2
1 Kunming Institute of Botany, Chinese Academy of Sciences, Heilongtan, Kunming 650204, China 2 Institut de Chimie des Substances Naturelles, UPR2301, CNRS, 91198 Gif-sur-Yvette cedex, France 3 UMR 7206-USM 104 Eco-anthropologie et ethnobiologie, MNHN, 75231 Paris cedex, France 4 Department of Botany, Makerere University, Box 7062, Kampala, Uganda 5 Chemistry Department, Makerere University, Box 7062, Kampala, Uganda
* Author to whom correspondence should be addressed.
Received: 28 August 2009 / Revised: 21 September 2009 / Accepted: 25 September 2009 / Published: 28 September 2009
Download PDF [104 KB, uploaded 18 June 2014]   |  

Abstract

One new drimane-type sesquiterpenoid, named ugandenial A (1), was isolated from the ethyl acetate extract of the bark of Warburgia ugandensis (Canellaceae) together with eight known drimane-type sesquiterpenoids: 11α-hydroxycinnamosmolide (2), warburganal (3), polygodial (4), mukaadial (5), dendocarbin A (6), 9α-hydroxycinnamolide (7), dendocarbin L (8) and dendocarbin M (9). Their structures were established by detailed spectroscopic analysis. In addition a keto-enol equilibrium was demonstrated for compound 1 through a detailed NMR analysis run in CD2Cl2 at 190 K. Cytotoxicity of the isolated compounds against KB cells was evaluated.
Keywords: Warburgia ugandensis; drimane-type sesquiterpenoid; ugandenial; cytotoxicity Warburgia ugandensis; drimane-type sesquiterpenoid; ugandenial; cytotoxicity
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
SciFeed

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
EndNote |
RIS
MDPI and ACS Style

Xu, M.; Litaudon, M.; Krief, S.; Martin, M.-T.; Kasenene, J.; Kiremire, B.; Dumontet, V.; Guéritte, F. Ugandenial A, a New Drimane-type Sesquiterpenoid from Warburgia ugandensis. Molecules 2009, 14, 3844-3850.

View more citation formats

Related Articles

Article Metrics

For more information on the journal, click here

Comments

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert