Next Article in Journal
Design and Synthesis of Immunoconjugates and Development of an Indirect ELISA for Rapid Detection of 3, 5-Dinitrosalicyclic Acid Hydrazide
Previous Article in Journal
Evaluation of Flavonoids and Furanocoumarins from Citrus bergamia (Bergamot) Juice and Identification of New Compounds
Molecules 2008, 13(9), 2229-2237; doi:10.3390/molecules13092229
Article

New Triterpene Glucosides from the Roots of Rosa laevigata Michx

1,2
,
2
,
1
,
2
,
2
,
2, 1,3,*  and 2,*
1 Guangxi Institute of Medicinal Plant, Nanning 530023, P.R. China 2 State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, P.R. China 3 Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100094, P.R. China
* Authors to whom correspondence should be addressed.
Received: 18 August 2008 / Revised: 11 September 2008 / Accepted: 12 September 2008 / Published: 22 September 2008
View Full-Text   |   Download PDF [288 KB, uploaded 18 June 2014]   |  

Abstract

Two new ursane-type triterpene glucosides, 2α,3α,24-trihydroxyurs-12,18-dien-28-oic acid β-D-glucopyranosyl ester (1) and 2α,3α,23-trihydroxyurs-12,19(29)-dien-28-oic acid β-D-glucopyranosyl ester (2), were isolated from the roots of Rosa laevigata, together with three known compounds: 2α,3β,19α-trihydroxyurs-12-en-28-oic acid β-Dglucopyranosyl ester (3), 2α,3α,19α-trihydroxyurs-12-en-28-oic acid β-D-glucopyranosyl ester (4) and 2α,3β,19α,23-tetrahydroxyurs-12-en-28-oic acid β-D-glucopyranosyl ester (5). The structures of new compounds were established on the basis of detailed 1D and 2D NMR spectroscopic analyses. Compounds 2 and 5 exhibited modest in vitro antifungal activities against Candida albicans and C. krusei.
Keywords: Ursane-type triterpene glucosides; Rosa laevigata; Antifungal activity Ursane-type triterpene glucosides; Rosa laevigata; Antifungal activity
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
SciFeed

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
EndNote |
RIS
MDPI and ACS Style

Yuan, J.-Q.; Yang, X.-Z.; Miao, J.-H.; Tang, C.-P.; Ke, C.-Q.; Zhang, J.-B.; Ma, X.-J.; Ye, Y. New Triterpene Glucosides from the Roots of Rosa laevigata Michx. Molecules 2008, 13, 2229-2237.

View more citation formats

Related Articles

Article Metrics

For more information on the journal, click here

Comments

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert