Molecules 2008, 13(9), 2229-2237; doi:10.3390/molecules13092229
Article

New Triterpene Glucosides from the Roots of Rosa laevigata Michx

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Received: 18 August 2008; in revised form: 11 September 2008 / Accepted: 12 September 2008 / Published: 22 September 2008
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Two new ursane-type triterpene glucosides, 2α,3α,24-trihydroxyurs-12,18-dien-28-oic acid β-D-glucopyranosyl ester (1) and 2α,3α,23-trihydroxyurs-12,19(29)-dien-28-oic acid β-D-glucopyranosyl ester (2), were isolated from the roots of Rosa laevigata, together with three known compounds: 2α,3β,19α-trihydroxyurs-12-en-28-oic acid β-Dglucopyranosyl ester (3), 2α,3α,19α-trihydroxyurs-12-en-28-oic acid β-D-glucopyranosyl ester (4) and 2α,3β,19α,23-tetrahydroxyurs-12-en-28-oic acid β-D-glucopyranosyl ester (5). The structures of new compounds were established on the basis of detailed 1D and 2D NMR spectroscopic analyses. Compounds 2 and 5 exhibited modest in vitro antifungal activities against Candida albicans and C. krusei.
Keywords: Ursane-type triterpene glucosides; Rosa laevigata; Antifungal activity
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MDPI and ACS Style

Yuan, J.-Q.; Yang, X.-Z.; Miao, J.-H.; Tang, C.-P.; Ke, C.-Q.; Zhang, J.-B.; Ma, X.-J.; Ye, Y. New Triterpene Glucosides from the Roots of Rosa laevigata Michx. Molecules 2008, 13, 2229-2237.

AMA Style

Yuan J-Q, Yang X-Z, Miao J-H, Tang C-P, Ke C-Q, Zhang J-B, Ma X-J, Ye Y. New Triterpene Glucosides from the Roots of Rosa laevigata Michx. Molecules. 2008; 13(9):2229-2237.

Chicago/Turabian Style

Yuan, Jing-Quan; Yang, Xin-Zhou; Miao, Jian-Hua; Tang, Chun-Ping; Ke, Chang-Qiang; Zhang, Ji-Bao; Ma, Xiao-Jun; Ye, Yang. 2008. "New Triterpene Glucosides from the Roots of Rosa laevigata Michx." Molecules 13, no. 9: 2229-2237.


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