Molecules 2008, 13(9), 2049-2057; doi:10.3390/molecules13092049
Article

New secoiridoid Glycosides from the Roots of Picrorhiza Scrophulariiflora

Lian-Chun Zou 1,2 , Tong-Fei Zhu 2,3 , Hua Xiang 2 email, Lu Yu 2 email, Zhi-Hui Yan 4 , Shu-Cai Gan 1 , Da-Cheng Wang 2,* email, Sheng Zeng 2  and Xu-Ming Deng 2,* email
1 College of Chemistry, Jilin University, Changchun 130062, P.R. China 2 College of Animal Science and Veterinary Medicine, Jilin University, Changchun 130062, P.R. China 3 Department of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, P.R. China 4 Chongqing Medical and Pharmaceutical College, Chongqing 400030, P.R. China
* Authors to whom correspondence should be addressed.
Received: 30 June 2008; in revised form: 27 August 2008 / Accepted: 28 August 2008 / Published: 1 September 2008
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Abstract: Three new secoiridoid glycosides, named picrogentiosides A (1), B (2) and C (3), have been isolated from the underground parts of Picrorhiza Scrophulariiflora, together with the two known compounds plantamajoside (4) and plantainoside D (5). Their structures were established by spectroscopic analyses and comparisons with data from related compounds. A pilot pharmacological study showed that picrogentiosides A (1) and B (2) have an immunomodulatory effect in vitro.
Keywords: Picrorhiza scrophulariiflora; Secoiridoid glycosides; Picrogentiosides A; B and C; Immunoenhancement

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Cite This Article

MDPI and ACS Style

Zou, L.-C.; Zhu, T.-F.; Xiang, H.; Yu, L.; Yan, Z.-H.; Gan, S.-C.; Wang, D.-C.; Zeng, S.; Deng, X.-M. New secoiridoid Glycosides from the Roots of Picrorhiza Scrophulariiflora. Molecules 2008, 13, 2049-2057.

AMA Style

Zou L-C, Zhu T-F, Xiang H, Yu L, Yan Z-H, Gan S-C, Wang D-C, Zeng S, Deng X-M. New secoiridoid Glycosides from the Roots of Picrorhiza Scrophulariiflora. Molecules. 2008; 13(9):2049-2057.

Chicago/Turabian Style

Zou, Lian-Chun; Zhu, Tong-Fei; Xiang, Hua; Yu, Lu; Yan, Zhi-Hui; Gan, Shu-Cai; Wang, Da-Cheng; Zeng, Sheng; Deng, Xu-Ming. 2008. "New secoiridoid Glycosides from the Roots of Picrorhiza Scrophulariiflora." Molecules 13, no. 9: 2049-2057.

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