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Advances of Modern Chromatographic and Electrophoretic Methods in Separation and Analysis of Flavonoids
Key Laboratory of Modern Chinese Medicines (China Pharmaceutical University), Ministry of Education; Nanjing 210009, P.R. China
* Author to whom correspondence should be addressed.
Received: 18 August 2008; in revised form: 30 September 2008 / Accepted: 7 October 2008 / Published: 16 October 2008
Abstract: Flavonoids, one of the largest groups of secondary metabolites, are widespread in vegetable crops such as herbs, fruits, vegetables, grains, seeds and derived foods such as juices, wines, oils, etc. They receive considerable attention due to their biological and physiological importance. Hundreds of publications on the analysis of flavonoids have appeared over the past decade. Traditional and more advanced techniques have come to prominence for sample preparation, separation, detection, and identification. This review intends to provide an updated, concise overview on the recent development and trends of separation, identification and quantification for flavonoids by modern chromatographic and spectrophotometric analytical techniques, including gas chromatography (GC), liquid chromatography (LC), and capillary electrophoresis (CE). The sample preparation before analysis is also briefly summarized.
Keywords: Flavonoids; Sample preparation; Separation; Analysis; Gas chromatography; Liquid chromatography; Capillary electrophoresis
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Liu, E.-H.; Qi, L.-W.; Cao, J.; Li, P.; Li, C.-Y.; Peng, Y.-B. Advances of Modern Chromatographic and Electrophoretic Methods in Separation and Analysis of Flavonoids. Molecules 2008, 13, 2521-2544.
Liu E-H, Qi L-W, Cao J, Li P, Li C-Y, Peng Y-B. Advances of Modern Chromatographic and Electrophoretic Methods in Separation and Analysis of Flavonoids. Molecules. 2008; 13(10):2521-2544.
Liu, E-Hu; Qi, Lian-Wen; Cao, Jun; Li, Ping; Li, Chang-Yin; Peng, Yong-Bo. 2008. "Advances of Modern Chromatographic and Electrophoretic Methods in Separation and Analysis of Flavonoids." Molecules 13, no. 10: 2521-2544.