Radical-scavenging Activity of the Reaction Products of Isoeugenol with Thiol, Thiophenol, Mercaptothiazoline or Mercaptomethylimidazole Using the Induction Period Method
Abstract
:Introduction
Results and Discussion
Radical scavenging activities determined by the induction period method
AIBN | BPO | |||
---|---|---|---|---|
Compound | Relative n | kinb/kp | Relative n | kinb/kp |
ISO-S-1 | 0.92 ± 0.05 | 36.43 ± 1.78 | 1.61 ± 0.08 | 8.88 ± 0.44 |
ISO-S-2 | 0.96 ± 0.04 | 34.81 ± 1.71 | 1.19 ± 0.05 | 11.75 ± 0.58 |
ISO-S-3 | 0.59 ± 0.02 | 56.63 ± 2.27 | 0.91 ± 0.04 | 15.46 ± 0.76 |
ISO-S-4 | 1.01 ± 0.05 | 32.86 ± 1.48 | 0.25 ± 0.01 | 55.95 ± 2.79 |
Isoeugenol | 1.11 ± 0.06 | 30.52 ± 1.36 | 1.75 ± 0.09 | 8.16 ± 0.42 |
Conclusions
Experimental
General
General procedure for the synthesis of ISO-S-1, 2, 3, and 4: reaction of isoeugenol (1) with thiols in the presence of Lewis acid
Reaction of 1 with thiophenol
Reaction of 1 with 2-mercaptothiazoline
Reaction of 1 with 2-mercapto-1-methylimidazole
DSC measurements
Rate of initiation
Measurement of stoichiometric factor (n)
Measurement of the inhibition rate constant (kinh)
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Kadoma, Y.; Kumada, W.; Asai, Y.; Sugita, Y.; Yokoe, I.; Fujisawa, S. Radical-scavenging Activity of the Reaction Products of Isoeugenol with Thiol, Thiophenol, Mercaptothiazoline or Mercaptomethylimidazole Using the Induction Period Method. Molecules 2007, 12, 1836-1844. https://doi.org/10.3390/12081836
Kadoma Y, Kumada W, Asai Y, Sugita Y, Yokoe I, Fujisawa S. Radical-scavenging Activity of the Reaction Products of Isoeugenol with Thiol, Thiophenol, Mercaptothiazoline or Mercaptomethylimidazole Using the Induction Period Method. Molecules. 2007; 12(8):1836-1844. https://doi.org/10.3390/12081836
Chicago/Turabian StyleKadoma, Yoshinori, Wakako Kumada, Yuhta Asai, Yoshiaki Sugita, Ichiro Yokoe, and Seiichiro Fujisawa. 2007. "Radical-scavenging Activity of the Reaction Products of Isoeugenol with Thiol, Thiophenol, Mercaptothiazoline or Mercaptomethylimidazole Using the Induction Period Method" Molecules 12, no. 8: 1836-1844. https://doi.org/10.3390/12081836