Molecules 2007, 12(8), 1771-1795; doi:10.3390/12081771
Review

Synthetic Approaches to Heterocyclic Ligands for Gd-Based MRI Contrast Agents

Received: 29 May 2007; in revised form: 3 August 2007 / Accepted: 3 August 2007 / Published: 9 August 2007
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Magnetic Resonance Imaging (MRI) methods are currently used in the clinic for the non invasive detection and characterization of a wide variety of pathologies. Increases in the diagnostic efficiency of MRI have been helped by both the design of dedicated MR sequences revealing specific aspects of the pathology and by the development of more sensitive and selective Contrast Agents (CAs), capable of more precisely delineating the borderline regions. In the present review we focus on the synthetic strategies used to obtain MRI CAs containing heterocyclic rings.
Keywords: Lanthanide Complexes; Contrast Agents; Heterocyclic Ligands; MR Imaging
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MDPI and ACS Style

Pérez-Mayoral, E.; Soler-Padrós, J.; Negri, V.; Cerdán, S.; Ballesteros, P. Synthetic Approaches to Heterocyclic Ligands for Gd-Based MRI Contrast Agents. Molecules 2007, 12, 1771-1795.

AMA Style

Pérez-Mayoral E, Soler-Padrós J, Negri V, Cerdán S, Ballesteros P. Synthetic Approaches to Heterocyclic Ligands for Gd-Based MRI Contrast Agents. Molecules. 2007; 12(8):1771-1795.

Chicago/Turabian Style

Pérez-Mayoral, Elena; Soler-Padrós, Jordi; Negri, Viviana; Cerdán, Sebastián; Ballesteros, Paloma. 2007. "Synthetic Approaches to Heterocyclic Ligands for Gd-Based MRI Contrast Agents." Molecules 12, no. 8: 1771-1795.

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