Molecules 2007, 12(5), 1064-1079; doi:10.3390/12051064
Article

Coordination Compounds Based on 1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic Acid

Received: 27 March 2007; in revised form: 11 May 2007 / Accepted: 11 May 2007 / Published: 21 May 2007
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Syntheses of 2,6-bis[((3S)-3-(methoxycarbonyl)-1,2,3,4-tetrahydroisoquinolin-2-yl)carbonyl]pyridine and its coordination compounds with Cu2+, Co2+, Co3+, or Fe3+ are described. By means of 1H- and 13C-NMR spectra it was proved that 2,6-bis[((3S)-3-(methoxycarbonyl)-1,2,3,4-tetrahydroisoquinolin-2-yl)carbonyl]pyridine as well as its coordination compound with Co3+ exist in the form of a mixture of three conformers, differing in the conformations at the two amide groups present. The prepared coordination compounds were tested in the enantioselective catalysis of the nitroaldol addition of nitromethane with 2-nitrobenzaldehyde or 4-nitrobenzaldehyde, and in the Michael addition of ethyl 2-oxocyclohexanecarboxylate to but-3-en-2-one.
Keywords: (S)-1; 2; 3; 4-Tetrahydroisoquinoline-3-carboxylic acid; chiral Tic acid derivatives; enantioselective catalysis; 2; 6-bis[((3S)-3-(methoxycarbonyl)-1; 2; 3; 4-tetra- hydroisoquinolin-2-yl)carbonyl]pyridine
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MDPI and ACS Style

Jansa, P.; Macháček, V.; Nachtigall, P.; Wsól, V.; Svobodová, M. Coordination Compounds Based on 1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic Acid. Molecules 2007, 12, 1064-1079.

AMA Style

Jansa P, Macháček V, Nachtigall P, Wsól V, Svobodová M. Coordination Compounds Based on 1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic Acid. Molecules. 2007; 12(5):1064-1079.

Chicago/Turabian Style

Jansa, Petr; Macháček, Vladimír; Nachtigall, Petr; Wsól, Vladimír; Svobodová, Markéta. 2007. "Coordination Compounds Based on 1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic Acid." Molecules 12, no. 5: 1064-1079.

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