Synthesis of 3,4,7,8-Tetrahydronaphthalene-1,5(2H,6H)-dione

doi:10.3390/12020183

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Molecules 2007, 12(2), 183-187; doi:10.3390/12020183

Article

Synthesis of 3,4,7,8-Tetrahydronaphthalene-1,5(2H,6H)-dione

Garrett B. Minne and Pierre J. De Clercq*

Ghent University, Department of Organic Chemistry, Laboratory for Organic Synthesis, Krijgslaan 281 (S4), B-9000 Gent, Belgium

* Author to whom correspondence should be addressed.

Received: 8 January 2007; in revised form: 9 February 2007 / Accepted: 11 February 2007 / Published: 13 February 2007

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Abstract: A short and high yielding route for thepreparation of the title compound, starting from commercially available1,5-dihydroxynaphthalene, is described. The key step in the sequence is the airoxidation of a bis(trimethylsilyloxy)diene precursor.

Keywords: 1; 5-Dihydroxynaphthalene;bis(trimethylsilyloxy)diene;air oxidation.

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MDPI and ACS Style

Minne, G.B.; De Clercq, P.J. Synthesis of 3,4,7,8-Tetrahydronaphthalene-1,5(2H,6H)-dione. Molecules 2007, 12, 183-187.

AMA Style

Minne GB, De Clercq PJ. Synthesis of 3,4,7,8-Tetrahydronaphthalene-1,5(2H,6H)-dione. Molecules. 2007; 12(2):183-187.

Chicago/Turabian Style

Minne, Garrett B.; De Clercq, Pierre J. 2007. "Synthesis of 3,4,7,8-Tetrahydronaphthalene-1,5(2H,6H)-dione." Molecules 12, no. 2: 183-187.

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