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• Bisio, A
• Pagano, B
• Romussi, A
• Bruno, O
• De Tommasi, N
• Romussi, G
• Mattia, CAndrea
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• Bisio, A
• Pagano, B
• Romussi, A
• Bruno, O
• De Tommasi, N
• Romussi, G
• Mattia, CAndrea
• [+] on PubMed
• Bisio, A
• Pagano, B
• Romussi, A
• Bruno, O
• De Tommasi, N
• Romussi, G
• Mattia, CAndrea

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Molecules 2007, 12(10), 2279-2287; doi:10.3390/12102279

Article

Relative Stereochemistry of a Diterpene from Salvia cinnabarina

Angela Bisio ¹ , Bruno Pagano ² , Alessia Romussi ³ , Olga Bruno ³ , Nunziatina De Tommasi ² , Giovanni Romussi ¹  and Carlo Andrea Mattia ^2,*

¹ Dipartimento di Chimica e Tecnologie Farmaceutiche e Alimentari, Università di Genova, Via Brigata Salerno, Genova, Italy ² Dipartimento di Scienze Farmaceutiche, Università di Salerno, Via Ponte Don Melillo, 84084 Fisciano, Salerno, Italy ³ Dipartimento di Scienze Farmaceutiche, Università di Genova, Viale Benedetto XV, Genova, Italy

* Author to whom correspondence should be addressed.

Received: 27 September 2007; in revised form: 5 October 2007 / Accepted: 5 October 2007 / Published: 10 October 2007

Download PDF Full-Text [155 KB, uploaded 2 October 2008 11:53 CEST]

Abstract: The relative stereochemistry of 3,4-secoisopimara-4(18),7,15-triene-3-oic acid, a diterpenoid with antispasmodic, hypotensive and antibacterial activities isolated from Salvia cinnabarina, was determined by an X-ray diffraction analysis of a single crystal of a suitable crystalline derivative.

Keywords: Salvia cinnabarina; Lamiaceae; secoisopimarane-diterpene; relative stereo- Salvia cinnabarina; Lamiaceae; secoisopimarane-diterpene; relative stereo-chemistry; X-ray structure.

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