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Molecules 2006, 11(9), 707-713; doi:10.3390/11090707
Article

Asymmetric Synthesis of (7aS)-7a-Methyl-4,5,7,7a-tetrahydro-1H-indene-2,6-dione and Useful Derivatives Thereof

,  and *
Ghent University, Department of Organic Chemistry, Laboratory for Organic Synthesis, Krijgslaan 281 (S4), B-9000 Gent, Belgium
* Author to whom correspondence should be addressed.
Received: 7 September 2006 / Revised: 14 September 2006 / Accepted: 14 September 2006 / Published: 18 September 2006
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Abstract

The enantioselective synthesis of the title compound, using Meyers' bicyclic lactam methodology, is described. This compound and a few of its derivatives are useful intermediates in natural product synthesis.
Keywords: Asymmetric synthesis; Meyers' bicyclic lactam template; hydrindenones. Asymmetric synthesis; Meyers' bicyclic lactam template; hydrindenones.
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Demin, S.; Van Haver, D.; De Clercq, P.J. Asymmetric Synthesis of (7aS)-7a-Methyl-4,5,7,7a-tetrahydro-1H-indene-2,6-dione and Useful Derivatives Thereof. Molecules 2006, 11, 707-713.

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