Molecules 2006, 11(5), 334-344; doi:10.3390/11050334
Article

An Improved NMR Study of Liposomes Using 1-Palmitoyl-2-oleoyl-sn-glycero-3-phospatidylcholine as Model

Oscar Cruciani 1 , Luisa Mannina 1,* email, Anatoli P. Sobolev 1 , Cesare Cametti 3  and AnnaLaura Segre 1
1 Istituto di Metodologie Chimiche, CNR, 00016 Monterotondo Stazione, Roma, Italy 2 Dipartimento S.T.A.A.M, Università degli Studi del Molise, 86100 Campobasso, Italy 3 Dipartimento di Fisica, Università di Roma "La Sapienza", piazz. A. Moro, 2, 00185 Roma, Italy and Istituto Nazionale per la Fisica della Materia (INFM), Unità di Roma1, Roma, Italy
* Author to whom correspondence should be addressed.
Received: 15 April 2006 / Accepted: 9 May 2006 / Published: 10 May 2006
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Abstract: In this paper we report a comparative characterization of Small UnilamellarVesicles (SUVs), Large Unilamellar Vesicles (LUVs) and Multilamellar Vesicles (MLVs)prepared from 1-palmitoyl-2-oleoyl-sn-glycero-3-phospatidylcholine (POPC), carried outusing two NMR techniques, namely High Resolution NMR in solution and HighResolution–Magic Angle Spinning (HR-MAS). The size and size distributions of thesevesicles were investigated using the dynamic light scattering technique. An improvedassignment of the 1H-NMR spectrum of MLVs is also reported.
Keywords: Liposomes; unilamellar vesicles; multilamellar vesicles; NMR; HR-MAS; dynamic light scattering

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MDPI and ACS Style

Cruciani, O.; Mannina, L.; Sobolev, A.P.; Cametti, C.; Segre, A. An Improved NMR Study of Liposomes Using 1-Palmitoyl-2-oleoyl-sn-glycero-3-phospatidylcholine as Model. Molecules 2006, 11, 334-344.

AMA Style

Cruciani O, Mannina L, Sobolev AP, Cametti C, Segre A. An Improved NMR Study of Liposomes Using 1-Palmitoyl-2-oleoyl-sn-glycero-3-phospatidylcholine as Model. Molecules. 2006; 11(5):334-344.

Chicago/Turabian Style

Cruciani, Oscar; Mannina, Luisa; Sobolev, Anatoli P.; Cametti, Cesare; Segre, AnnaLaura. 2006. "An Improved NMR Study of Liposomes Using 1-Palmitoyl-2-oleoyl-sn-glycero-3-phospatidylcholine as Model." Molecules 11, no. 5: 334-344.

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