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Molecules 2005, 10(10), 1298-1306; doi:10.3390/10101298
Article

Pyrazolo[4,3-e][1,2,4]triazines: Purine Analogues with Electronic Absorption in the Visible Region

1, 1,*  and 2
Received: 12 April 2005; Accepted: 10 July 2005 / Published: 31 October 2005
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Abstract: Synthesis of several pryrazolo[4,3-e][1,2,4]-triazines is described. Theabsorption spectrum of some 5-substituted derivatives was found to extend to the visibleregion. These compounds were found to inhibit some enzymes of purine metabolism, likexanthine oxidase or bacterial purine-nucleoside phosphorylase with Ki values in the 10-3 –10-5 M range.
Keywords: Pyrazolo[4; 3-e][1; 2; 4]triazines; purine analogues; enzyme inhibitors. Pyrazolo[4; 3-e][1; 2; 4]triazines; purine analogues; enzyme inhibitors.
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Mojzych, M.; Rykowski, A.; Wierzchowski, J. Pyrazolo[4,3-e][1,2,4]triazines: Purine Analogues with Electronic Absorption in the Visible Region. Molecules 2005, 10, 1298-1306.

AMA Style

Mojzych M, Rykowski A, Wierzchowski J. Pyrazolo[4,3-e][1,2,4]triazines: Purine Analogues with Electronic Absorption in the Visible Region. Molecules. 2005; 10(10):1298-1306.

Chicago/Turabian Style

Mojzych, Mariusz; Rykowski, Andrzej; Wierzchowski, Jacek. 2005. "Pyrazolo[4,3-e][1,2,4]triazines: Purine Analogues with Electronic Absorption in the Visible Region." Molecules 10, no. 10: 1298-1306.



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