Next Article in Journal
Application of Divergence Entropy to Characterize the Structure of the Hydrophobic Core in DNA Interacting Proteins
Previous Article in Journal
Thermodynamic Analysis of a Waste Heat Driven Vuilleumier Cycle Heat Pump
Previous Article in Special Issue
Self-oscillating Water Chemiluminescence Modes and Reactive Oxygen Species Generation Induced by Laser Irradiation; Effect of the Exclusion Zone Created by Nafion
Article Menu

Export Article

Open AccessArticle
Entropy 2015, 17(3), 1466-1476;

The Solute-Exclusion Zone: A Promising Application for Mirofluidics

Bioengineering Department, University of California, Merced, CA 94343, USA
MicroBase Technology Corp., Bade City, Taoyuan, 33464, Taiwan
Center for Biomedical Engineering, Chang Gung University, Taoyuan, 33302, Taiwan
Author to whom correspondence should be addressed.
Received: 1 July 2014 / Revised: 9 March 2015 / Accepted: 16 March 2015 / Published: 23 March 2015
(This article belongs to the Special Issue Entropy and EZ-Water)
View Full-Text   |   Download PDF [3049 KB, uploaded 23 March 2015]


While unique phenomena exist at fluid-solid phase intersections, many interfacial phenomena manifest solely on limited scales—i.e., the nm-mm ranges—which stifles their application potential. Here, we constructed microfluidic chips that utilize the unique long-distance interface effects of the Solute-Exclusion Zone (EZ) phenomenon to mix, separate, and guide samples in desired directions within microfluidic channels. On our “EZ Chip”, we utilized the interfacial force generated by EZs to transport specimens across streamlines without the need of an off-chip power source. The advantages of easy-integration, low fabrication cost, and no off-chip energy input make the EZ suitable for independent, portable lab-on-chip system applications. View Full-Text
Keywords: water; solute-exclusion; EZ; microfluidics water; solute-exclusion; EZ; microfluidics
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Share & Cite This Article

MDPI and ACS Style

Chen, C.-S.; Farr, E.; Anaya, J.M.; Chen, E.Y.-T.; Chin, W.-C. The Solute-Exclusion Zone: A Promising Application for Mirofluidics. Entropy 2015, 17, 1466-1476.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Entropy EISSN 1099-4300 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top