Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
5.4
3.9
Journals
JCM
Special Issues
Targeted Treatment in Head–Neck Cancer
share announcement

Targeted Treatment in Head–Neck Cancer

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Otolaryngology".

Deadline for manuscript submissions: 31 August 2024 | Viewed by 817

Special Issue Editors

Dr. Jacopo Zocchi

E-Mail Website
Guest Editor
Division of Otolaryngology and Head and Neck Surgery, European Institute of Oncology IRCCS, 20142 Milan, Italy
Interests: endoscopes; skull base; cancer; head and neck surgery; otolaryngology; larynx
Dr. Gerardo Petruzzi

E-Mail
Guest Editor
Department of Otolaryngology Head and Neck Surgery, Regina Elena National Cancer Institute IRCCS, 00144 Rome, Italy
Interests: head and neck cancer; robotic surgery; oropharyngeal cancer; laryngeal cancer; rare neoplasm in head and neck
Dr. Pietro De Luca

E-Mail Website
Guest Editor
Fatebenefratelli Isola Tiberina—Gemelli Isola Hospital, 00100 Rome, Italy
Interests: otolaryngology; smell and taste; head and neck cancer; pediatric otolaryngology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue to explore the advancements and challenges in personalized and precision medicine approaches for the management of head and neck cancer. This Special Issue invites original research articles that delve into various aspects of targeted treatment for head–neck cancer. We encourage submissions focusing on novel targeted therapies, immunotherapy and other precision medicine approaches that address the unique characteristics of head and neck tumors.

We seek comprehensive research articles, clinical studies, experimental investigations and translational studies that shed light on the latest developments in targeted treatment within the field of head–neck cancer. However, please note that this Special Issue will not consider mini-reviews or case reports.

We look forward to receiving your submissions and contributing to the collective understanding of targeted treatment potential in improving outcomes for patients with head and neck cancer.

Dr. Jacopo Zocchi
Dr. Gerardo Petruzzi
Dr. Pietro De Luca
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • head and neck squamous cell carcinoma
  • precision medicine
  • targeted therapies
  • immunotherapy
  • tumor heterogeneity
  • treatment response monitoring

Published Papers (2 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

Jump to: Review

18 pages, 2845 KiB  
Article
Quality of Life and Respiratory Performance in the Laryngectomized Patient: Role of the HME Filters during Physical Activity
by Massimo Mesolella, Salvatore Allosso, Mauro Mormile, Giuseppe Quaremba, Veronica Errante, Roberto D’Aniello, Giovanni Motta, Vincenzo Catalano, Gaetano Motta and Grazia Salerno
J. Clin. Med. 2024, 13(11), 3137; https://doi.org/10.3390/jcm13113137 - 27 May 2024
Viewed by 223
Abstract
Background: Permanent tracheostomy because of total laryngectomy surgery entails significant consequences for patients regarding respiratory physiopathology, such as the loss of the filtering, humidifying, and heating of air by the nose. The use of special stomal filters can provide adequate protection of the [...] Read more.
Background: Permanent tracheostomy because of total laryngectomy surgery entails significant consequences for patients regarding respiratory physiopathology, such as the loss of the filtering, humidifying, and heating of air by the nose. The use of special stomal filters can provide adequate protection of the tracheal–bronchopulmonary system with a reduction in respiratory pathologies. In fact, in most cases, laryngectomy patients are first cigarette smokers who for this reason also already have respiratory diseases such as chronic obstructive pulmonary disease (COPD). Despite the availability of tracheal filters, as reported in the literature, patients often tend to limit their use due to reported breathing difficulties, especially in conditions of intense breathing. Methods: The objective of this clinical study was to evaluate the most suitable stomal filter for laryngectomy patients during physical activity. The filters studied were an INHEALTH device (Blom-Singer SpeakFree HME); two ATOS devices (Provox® Life™ Energy HME and Provox® Life™ Home HME); and an FAHL device (Laryvox HME Sport). Results: For this purpose, the performances of 31 laryngectomy patients, subjected to medium–high physical effort, were analyzed through a standardized pneumological test, the Six Minute Walking Test (6MWT), which involves a sustained walk lasting six minutes, with an evaluation of heart rate, oxygen saturation, and meters traveled every 60 s; furthermore, we examined two subjective indices, namely, the basal and final dyspnea index and the initial and final muscular fatigue index. Conclusions: The multidisciplinary approach of the laryngectomee patient must also take pulmonary rehabilitation into consideration. It is the task of the medical team and speech therapy support to help the patient in the correct choice of HME filters taking into account daily needs. Full article
(This article belongs to the Special Issue Targeted Treatment in Head–Neck Cancer)
►▼ Show Figures

Figure 1

Review

Jump to: Research

19 pages, 318 KiB  
Review
Stereotactic Body Radiotherapy in Recurrent and Oligometastatic Head and Neck Tumours
by Jodie L. M. Tham, Sweet Ping Ng, Richard Khor, Morikatsu Wada, Hui Gan, Alesha A. Thai, June Corry, Houda Bahig, Antti A. Mäkitie, Sandra Nuyts, Remco De Bree, Primož Strojan, Wai Tong Ng, Avraham Eisbruch, James C. H. Chow and Alfio Ferlito
J. Clin. Med. 2024, 13(11), 3020; https://doi.org/10.3390/jcm13113020 - 21 May 2024
Viewed by 384
Abstract
The treatment of head and neck cancers (HNCs) encompasses a complex paradigm involving a combination of surgery, radiotherapy, and systemic treatment. Locoregional recurrence is a common cause of treatment failure, and few patients are suitable for salvage surgery. Reirradiation with conventional radiation techniques [...] Read more.
The treatment of head and neck cancers (HNCs) encompasses a complex paradigm involving a combination of surgery, radiotherapy, and systemic treatment. Locoregional recurrence is a common cause of treatment failure, and few patients are suitable for salvage surgery. Reirradiation with conventional radiation techniques is challenging due to normal tissue tolerance limits and the risk of significant toxicities. Stereotactic body radiotherapy (SBRT) has emerged as a highly conformal modality that offers the potential for cure while limiting the dose to surrounding tissue. There is also growing research that shows that those with oligometastatic disease can benefit from curative intent local ablative therapies such as SBRT. This review will look at published evidence regarding the use of SBRT in locoregional recurrent and oligometastatic HNCs. Full article
(This article belongs to the Special Issue Targeted Treatment in Head–Neck Cancer)
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-2
Back to TopTop