In this paper, we present a finite-element simulation of an adaptive piezoelectric fluid-membrane lens for which we modelled the fluid-structure interaction and resulting membrane deformation in COMSOL Multiphysics^®. Our model shows the explicit coupling of the piezoelectric physics with the fluid dynamics physics to simulate the interaction between the piezoelectric and the fluid forces that contribute to the deformation of a flexible membrane in the adaptive lens. Furthermore, the simulation model is extended to describe the membrane deformation by additional fluid forces from the fluid thermal expansion. Subsequently, the simulation model is used to study the refractive power of the adaptive lens as a function of internal fluid pressure and analyze the effect of the fluid thermal expansion on the refractive power. Finally, the simulation results of the refractive power are compared to the experimental results at different actuation levels and temperatures validating the coupled COMSOL model very well. This is explicitly proven by explaining an observed positive drift of the refractive power at higher temperatures. Full article

The phenomenon of electro-osmosis was studied by performing numerical simulations on the flow between parallel walls and at the nozzle microchannels. In this work, we propose a numerical approximation to perform simulations of vortex formation which occur after the passage of the fluid through an abrupt contraction at the microchannel. The motion of the charges in the solution is described by the Poisson–Nernst–Planck equations and used the generalized finite differences to solve the numerical problem. First, solutions for electro-osmotic flow were obtained for the Phan–Thien/Thanner model in a parallel walls channel. Later simulations for electro-osmotic flow were performed in a nozzle. The formation of vortices near the contraction within the nozzle was verified by taking into account a flow perturbation model. Full article

Carrier-free enzyme immobilization techniques are an important development in the field of efficient and streamlined continuous synthetic processes using microreactors. Here, the use of monolithic, self-assembling all-enzyme hydrogels is expanded to phenolic acid decarboxylases. This provides access to the continuous flow production of p-hydroxystyrene from p-coumaric acid for more than 10 h with conversions ≥98% and space time yields of 57.7 g·(d·L)⁻¹. Furthermore, modulation of the degree of crosslinking in the hydrogels resulted in a defined variation of the rheological behavior in terms of elasticity and mesh size of the corresponding materials. This work is addressing the demand of sustainable strategies for defunctionalization of renewable feedstocks. Full article