Special Issues

Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Eye Diseases: Diagnosis and Management—2nd Edition
edited by
submission deadline 30 Sep 2025 | 20 articles | Viewed by 40400 | Submission Open
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Machine-Learning-Based Disease Diagnosis and Prediction
edited by Fakhar Abbas
submission deadline 30 Sep 2025 | 18 articles | Viewed by 28504 | Submission Open
Keywords: development and validation of machine learning models for disease diagnosis and prediction; integration of multimodal data (e.g.; imaging; genomic; and clinical) for enhanced diagnostic accuracy; artificial intelligence in healthcare; ethical and regulatory considerations in the deployment of machine learning for healthcare applications; case studies and applications of machine learning in specific disease domains (e.g.; cancer; cardiovascular diseases; and neurodegenerative disorders); comparative studies and benchmarking of machine learning approaches for disease diagnosis and prediction; healthcare analytics; bioinformatics; medical imaging analysis
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Deep Learning in Medical and Biomedical Image Processing
edited by
submission deadline 30 Sep 2025 | 8 articles | Viewed by 26660 | Submission Open
Keywords: deep learning; medical and biomedical image processing; model explainability and evaluation; generative model; machine learning
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Imaging Diagnosis in Abdomen, 2nd Edition submission deadline 30 Sep 2025 | 8 articles | Viewed by 21598 | Submission Open
Keywords: ultrasound computed tomography; MR imaging; PET imaging diagnosis; oncologic imaging; therapeutic response assessment; biomarkers; multidisciplinary management
(This special issue belongs to the Section Medical Imaging and Theranostics)
New Diagnostic and Testing Strategies for Infectious Diseases
edited by
submission deadline 30 Sep 2025 | 8 articles | Viewed by 20503 | Submission Open
Keywords: infectious diseases diagnosis; clinical laboratory techniques; molecular biology; infection control; virulence
(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)
Respiratory Diseases: Diagnosis and Management
edited by Ori Wand and
submission deadline 30 Sep 2025 | 12 articles | Viewed by 19734 | Submission Open
Keywords: interstitial lung diseases; chronic obstructive pulmonary disease; asthma; COVID-19; lung cancer; interventional pulmonology
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Periodontal Disease: Diagnosis and Management submission deadline 30 Sep 2025 | 7 articles | Viewed by 13238 | Submission Open
Keywords: periodontal disease; periodontitis; management; diagnosis; biomarker; periodontology
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Advances in Endoscopy submission deadline 30 Sep 2025 | 6 articles | Viewed by 13199 | Submission Open
(This special issue belongs to the Section Medical Imaging and Theranostics)
Advances in Laboratory Markers of Human Disease
edited by
submission deadline 30 Sep 2025 | 8 articles | Viewed by 12068 | Submission Open
Keywords: laboratory biomarkers; genomic; proteomics; molecular diagnostics; clinical chemistry  
(This special issue belongs to the Section Clinical Laboratory Medicine)
Challenges in Urology: From the Diagnosis to the Management submission deadline 30 Sep 2025 | 6 articles | Viewed by 10753 | Submission Open
Keywords: challenges; complications; rare; surgery; cancer
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
The Future of Diagnostics: Exploring the Role of Artificial Intelligence in Medicine
edited by , Neil Vaughan and Jiaxiang Zhang
submission deadline 30 Sep 2025 | 4 articles | Viewed by 10259 | Submission Open
Keywords: diagnostics; artificial intelligence; medicine; healthcare; future
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Imaging for the Diagnosis of Obstetric and Gynecological Diseases
edited by
submission deadline 30 Sep 2025 | 5 articles | Viewed by 8692 | Submission Open
Keywords: diagnosis; imaging; gynecology and obstetrics; gynecological cancer; hysteroscopy; ovarian disease
(This special issue belongs to the Section Medical Imaging and Theranostics)
Diagnostic Imaging in Gastrointestinal and Liver Diseases
edited by and
submission deadline 30 Sep 2025 | 5 articles | Viewed by 7858 | Submission Open
Keywords: ultrasonography; elastography; multiparametric ultrasound; contrast-enhanced ultrasound; endoscopic ultrasound; contrast-enhanced endoscopic ultrasound; computer tomography; magnetic resonance imaging; gastrointestinal diseases; diffuse liver disease; focal liver lesions
(This special issue belongs to the Section Medical Imaging and Theranostics)
Recent Advancements in the Diagnostics of Prostatitis submission deadline 30 Sep 2025 | 4 articles | Viewed by 6878 | Submission Open
Keywords: prostatitis; diagnostics; biomarkers; microbiology; imaging technologies; MRI; ultrasound; precision medicine; inflammatory proteins; genetic markers; artificial intelligence
(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)
New Trends in the Diagnosis of Gynecological and Obstetric Diseases
edited by and Laurentiu Pirtea
submission deadline 30 Sep 2025 | 4 articles | Viewed by 6804 | Submission Open
Keywords: obstetrics and gynecology diagnostics; screening; artificial intelligence; test accuracy
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Recent Advances in Breast Cancer Imaging
edited by
submission deadline 30 Sep 2025 | 4 articles | Viewed by 6518 | Submission Open
Keywords: breast cancer; neoadjuvant chemotherapy; axillary lymph nodes; molecular subtypes; hormonal receptor positive; medical oncology; breast surgery; breast cancer metastasis; pathological complete response; breast cancer recurrence
(This special issue belongs to the Section Medical Imaging and Theranostics)
Advanced Musculoskeletal Imaging in Clinical Diagnostics
edited by
submission deadline 30 Sep 2025 | 6 articles | Viewed by 6483 | Submission Open
Keywords: musculoskeletal imaging; cancer imaging; textural analysis; radiomics; MRI; CT; PET
(This special issue belongs to the Section Medical Imaging and Theranostics)
Artificial Intelligence in the Diagnostics of Dental Diseases, 2nd Edition
edited by Hakan Turkkahraman
submission deadline 30 Sep 2025 | 4 articles | Viewed by 6170 | Submission Open
Keywords: artificial intelligence; machine learning; neural networks; dental diseases; clinical decision support systems; medical diagnosis
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Advances in Diagnosis and Management of Oral Disorders
edited by
submission deadline 30 Sep 2025 | 6 articles | Viewed by 5670 | Submission Open
Keywords: oral disease; biomarker; prognosis; periodontal disease; machine learning; MRI; CBCT
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Diagnostic Imaging in Neurological Diseases
edited by
submission deadline 30 Sep 2025 | 8 articles | Viewed by 5648 | Submission Open
Keywords: diagnostic imaging; neurological diseases/disorders; central nervous system; imaging techniques; magnetic resonance imaging (MRI); positron emission tomography (PET); diagnostic modalities
(This special issue belongs to the Section Medical Imaging and Theranostics)
Artificial Intelligence Application in Cornea and External Diseases submission deadline 30 Sep 2025 | 3 articles | Viewed by 5392 | Submission Open
Keywords: artificial intelligence; machine learning; cornea; ocular surface; ophthalmology; external eye diseases; mobile health; telemedicine
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Diagnosis and Management of Metabolic Bone Diseases: 2nd Edition submission deadline 30 Sep 2025 | 5 articles | Viewed by 5373 | Submission Open
Keywords: inborn errors of metabolism; inherited metabolic diseases; bone metabolism/health; short stature; skeletal; disturbances in calcium and phosphorus metabolism; hypophosphatemic rickets; hypophosphatasia
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Advances in Diagnostic and Therapeutic Strategies for Infectious Diseases
edited by
submission deadline 30 Sep 2025 | 4 articles | Viewed by 5049 | Submission Open
Keywords: infectious diseases; diagnostic advancements; therapeutic strategies; antimicrobial resistance; molecular diagnostics; clinical management; emerging pathogens; precision medicine
(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)
Radiomics in Oncology
edited by
submission deadline 30 Sep 2025 | 2 articles | Viewed by 5016 | Submission Open
Keywords: radiomics; oncology; artificial intelligence; precision medicine; texture analysis; imaging
(This special issue belongs to the Section Medical Imaging and Theranostics)
Advances in Inflammation and Infection Imaging
edited by
submission deadline 30 Sep 2025 | 4 articles | Viewed by 4754 | Submission Open
Keywords: imaging; infection; inflammation; radiology; nuclear medicine; molecular imaging; hybrid imaging
(This special issue belongs to the Section Medical Imaging and Theranostics)
Diagnosis and Management of Ophthalmic Disorders
edited by Assaf Kratz
submission deadline 30 Sep 2025 | 6 articles | Viewed by 4725 | Submission Open
Keywords: ocular diseases; early diagnosis; advanced imaging; glaucoma; age-related macular degeneration; diabetic retinopathy
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Brain/Neuroimaging 2025
edited by Ronald Antulov
submission deadline 30 Sep 2025 | 4 articles | Viewed by 4602 | Submission Open
Keywords: advanced neuroimaging; dual-energy CT; photon-counting CT; perfusion MRI; MRI fingerprinting; brain lesions; neurodegenerative disorders; brain imaging; diagnosis; prognosis
(This special issue belongs to the Section Medical Imaging and Theranostics)
Medical Imaging in Diagnosis, Prevention and Rehabilitation of Musculoskeletal Injuries
edited by , W. Catherine Cheung and Suguna Pappu
submission deadline 30 Sep 2025 | 3 articles | Viewed by 4368 | Submission Open
Keywords: fitting of prostheses and exoskeletons; force-based manipulations; medical imaging (e.g.; MRI; CT; ultrasound elastography); musculoskeletal pain (low-back pain and non-specific causes of chronic pain); myofascial pain syndrome; sports training; surgical scar and postoperative management; thermal and non-thermal modalities
(This special issue belongs to the Section Medical Imaging and Theranostics)
Advances in Elastography for Applications in Rehabilitation, Physiotherapy, and Sports Sciences submission deadline 30 Sep 2025 | 3 articles | Viewed by 4287 | Submission Open
Keywords: elastography; shear wave elastography; ultrasound imaging; physiotherapy; rehabilitation; musculoskeletal system
(This special issue belongs to the Section Medical Imaging and Theranostics)
Latest Advances in Ophthalmic Imaging submission deadline 30 Sep 2025 | 4 articles | Viewed by 4054 | Submission Open
Keywords: optical coherence tomography (OCT); adaptive optics imaging; fundus photography; multimodal imaging; artificial intelligence (AI) in ophthalmic imaging
(This special issue belongs to the Section Medical Imaging and Theranostics)
Rare Diseases: Diagnosis and Management
edited by
submission deadline 30 Sep 2025 | 3 articles | Viewed by 3919 | Submission Open
Keywords: rare diseases; diagnosis; treatment; management; technology; therapeutics; patient outcomes
(This special issue belongs to the Section Clinical Laboratory Medicine)
Diagnosis and Management of Postural Disorders
edited by
submission deadline 30 Sep 2025 | 2 articles | Viewed by 3709 | Submission Open
Keywords: Scoliosis; Spinal deformity; Kyphosis; Faulty posture; Bad posture; Children; Adolescents; Adults; Screening; Prevention; Outcomes; Person-centred outcomes; Diagnostic imaging; Function; Functional tests
(This special issue belongs to the Section Medical Imaging and Theranostics)
Integrative Approaches in Head and Neck Cancer Imaging
edited by
submission deadline 30 Sep 2025 | 2 articles | Viewed by 3665 | Submission Open
Keywords: head and neck cancer; imaging technologies; multimodal imaging; image-guided therapy; artificial intelligence in imaging
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Exploring the Role of Diagnostic Biochemistry, 2nd Edition
edited by Daria Pašalić and Lidija Bilic-Zulle
submission deadline 30 Sep 2025 | 2 articles | Viewed by 3433 | Submission Open
Keywords:   laboratory tests in diagnosis; prognosis; monitoring; and treatment;   blood biomarkers in laboratory medicine;   extravascular body fluid biomarkers in laboratory medicine;   novel biomarkers in clinical biochemistry;   evidence-based laboratory medicine;   extra analytical phases and patient safety;   quality assurance and management in laboratory medicine
(This special issue belongs to the Section Clinical Laboratory Medicine)
Confocal Microscopy: Clinical Impacts and Innovation, 2nd Edition submission deadline 30 Sep 2025 | 2 articles | Viewed by 3231 | Submission Open
Keywords: confocal laser endomicroscopy; diagnosis; biopsy specimens; tumor; cell imaging; deep machine learning techniques
(This special issue belongs to the Section Biomedical Optics)
New Insights into the Diagnosis and Prognosis of Eye Diseases submission deadline 30 Sep 2025 | 3 articles | Viewed by 3053 | Submission Open
Keywords: diagnosis; prognosis; eye diseases; markers; clinical practice and patient care
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
DNA Sequencing of Infectious Diseases submission deadline 30 Sep 2025 | 2 articles | Viewed by 2984 | Submission Open
Keywords: DNA sequencing; infectious disease; diagnostics; screening; whole-genome sequencing; targeted amplicon sequencing
(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)
AI Transparency in Digital Pathology
edited by and Gavino Faa
submission deadline 30 Sep 2025 | 1 articles | Viewed by 2691 | Submission Open
Keywords: digital pathology; artificial intelligence; explainability; reproducibility; whole-slide image; feature extraction; deep learning; machine learning; image analysis
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Inflammatory and Infectious Skin Diseases: From Diagnostics to Management
edited by , and Valeria Gaspari
submission deadline 30 Sep 2025 | 3 articles | Viewed by 2668 | Submission Open
Keywords: inflammatory skin diseases; infectious skin diseases; dermatological diagnostics; therapeutic management; skin infection biomarkers; immune-mediated skin disorders; clinical dermatology; precision medicine in dermatology
(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)
Vulvovaginal Disorders: The Critical Role of Accurate Diagnosis to Effective Management Strategies
edited by Orna Reichman and
submission deadline 30 Sep 2025 | 1 articles | Viewed by 2104 | Submission Open
Keywords: diagnosis; screening; marker; prognosis; vulvovaginal disorders; pathology; theranostics
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Advanced Pathology and Diagnostics in Gastroenterology and Liver Diseases 2025
edited by
submission deadline 30 Sep 2025 | 1 articles | Viewed by 1995 | Submission Open
Keywords: diagnosis; screening; marker; prognosis; machine learning; gastroenterology; hepatology; pathology; theranostics; endoscopic image
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Advances in the Use of Artificial Intelligence for the Diagnosis and Management of Hand Conditions
edited by
submission deadline 30 Sep 2025 | 1 articles | Viewed by 1513 | Submission Open
Keywords: artificial intelligence; machine learning; hand conditions; preoperative diagnosis; postoperative prognosis; surgical outcomes; imaging techniques
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Innovations in Hepatobiliary and Pancreatic Cancer Diagnosis: Recent Developments
edited by
submission deadline 30 Sep 2025 | 2 articles | Viewed by 1395 | Submission Open
Keywords: diagnosis; screening; marker; prognosis; hepatobiliary and pancreatic cancer; pathology; theranostics; endoscopic image
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Classification of Diseases Using Machine Learning Algorithms: 2nd Edition
edited by
submission deadline 30 Sep 2025 | 2 articles | Viewed by 1382 | Submission Open
Keywords: artificial intelligence; classification of diseases; machine learning; medical image processing; deep learning; neural network; decision support systems
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Histopathology in Cancer Diagnosis and Prognosis—2nd Edition
edited by
submission deadline 30 Sep 2025 | 1 articles | Viewed by 1355 | Submission Open
Keywords: cancer; precision medicine; histopathology; diagnosis; prognostic/predictive markers
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Advancements in Craniofacial Practices: Imaging, AI, Surgery, and Patient Care
edited by
submission deadline 30 Sep 2025 | 2 articles | Viewed by 1345 | Submission Open
Keywords: craniofacial imaging; 3D radiological imaging; 3D photogrammetry; 4D stereophotogrammetry; artificial intelligence (AI); craniofacial surgery; patient-centered care; 3D printing; precision medicine; telehealth; surgical planning; interdisciplinary collaboration
(This special issue belongs to the Section Medical Imaging and Theranostics)
Advances in the Diagnosis and Management of Idiopathic Normal Pressure Hydrocephalus submission deadline 30 Sep 2025 | 1 articles | Viewed by 1076 | Submission Open
Keywords: idiopathic normal pressure hydrocephalus (iNPH); neurological disorder; ventricular enlargement; cerebrospinal fluid (CSF) dynamics; cognitive impairment; gait disturbance
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Diagnosis and Management of Gynecological Diseases: Advancements and Challenges
edited by
submission deadline 30 Sep 2025 | 1 articles | Viewed by 1064 | Submission Open
Keywords: gynecology; diagnosis; new technologies; female; women diseases; new approaches; genital pathology; reproductive medicine
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Clinical Applications of CT and MRI
edited by
submission deadline 30 Sep 2025 | 1 articles | Viewed by 1035 | Submission Open
Keywords: CT; MRI; diagnosis; prognosis; oncology; neurology
(This special issue belongs to the Section Medical Imaging and Theranostics)
Biomarkers of Gynecological Cancers
edited by
submission deadline 30 Sep 2025 | 1 articles | Viewed by 896 | Submission Open
Keywords: biomarkers; gynecological cancer; cervical cancer; ovarian cancer; uterine cancer; endometrial cancer
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
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