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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Applications of PET/CT in Clinical Diagnostics

edited by Jasna M. Mihailovic and Partha S Choudhury

submission deadline 13 Nov 2025 | 4 articles | Viewed by 8363 | Submission Open

Keywords: F-18; fluorodeoxyglucose; PET/CT imaging; oncology; radiotracers beyond F-18 fluorodeoxyglucose; clinical diagnostics

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in the Laboratory Diagnosis

edited by

Giuseppe Lippi

and Camilla Mattiuzzi

submission deadline 30 Nov 2025 | 12 articles | Viewed by 37056 | Submission Open

Keywords: laboratory diagnosis; biomarkers; clinical chemistry; laboratory analysis; artificial intelligence

(This special issue belongs to the Section Clinical Laboratory Medicine)

Advances in the Diagnosis and Management of Pediatric Diseases

edited by

Elena Tarca

submission deadline 30 Nov 2025 | 13 articles | Viewed by 25656 | Submission Open

Keywords: pediatrics; pediatric surgery; neonatal medicine; congenital malformations; pediatric trauma; pediatric oncology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Research Update on Nuclear Medicine

edited by

Francesco Dondi

submission deadline 30 Nov 2025 | 6 articles | Viewed by 22353 | Submission Open

Keywords: nuclear medicine; diagnostic radiology; PET/CT; SPECT; PET; imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in the Diagnosis and Treatment of Infections of the Central Nervous System

edited by

Teresa Perillo

and Raffaella Capasso

submission deadline 30 Nov 2025 | 1 articles | Viewed by 21712 | Submission Open

Keywords: central nervous system infections; meningitis; HIV; tuberculosis; magnetic resonance imaging

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Artificial Intelligence for Health and Medicine

edited by

Daniele Giansanti

submission deadline 30 Nov 2025 | 14 articles | Viewed by 19405 | Submission Open

Keywords: artificial intelligence; deep learning; healthcare; image segmentation; disease prediction; monitoring

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Recent Advances in Diagnosis and Treatment of Kidney Diseases: 2nd Edition

edited by

Kenji Tsuji

submission deadline 30 Nov 2025 | 4 articles | Viewed by 17490 | Submission Open

Keywords: chronic kidney disease; diabetic kidney disease; glomerulonephritis; polycystic kidney diseases; renal pathology; biomarker; kidney regeneration; hemodialysis; peritoneal dialysis; diagnosis

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Vascular Diagnostic Imaging

edited by

Hyo-Suk Ahn

submission deadline 30 Nov 2025 | 4 articles | Viewed by 16437 | Submission Open

Keywords: flow-mediated dilation (FMD); optical coherence tomography (OCT); intravascular ultrasound (IVUS)

(This special issue belongs to the Section Medical Imaging and Theranostics)

Artificial Intelligence and Pattern Recognition Methods for the Automatic Detection and Evaluation of Neurological Disorders, 2nd Edition

edited by

Juan Rafael Orozco-Arroyave

submission deadline 30 Nov 2025 | 7 articles | Viewed by 14247 | Submission Open

Keywords: machine learning; neurodegenerative diseases; diagnosis; detection and evaluation; monitoring

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Hematology: Diagnostic Techniques and Assays

edited by Chihyun Cho

submission deadline 30 Nov 2025 | 5 articles | Viewed by 12101 | Submission Open

Keywords: diagnostic; hematology; technique; assay; blood; genetic; molecular

(This special issue belongs to the Section Clinical Laboratory Medicine)

Diagnosis and Management of Arrhythmias

edited by

Laura Vitali-Serdoz

Martina Nesti

and Dirk Bastian

submission deadline 30 Nov 2025 | 6 articles | Viewed by 11117 | Submission Open

Keywords: arrhythmia; electrocardiogram (ECG); cardiac implantable devices; antiarrhythmic drugs; cardiac monitoring; implantable loop recorder; digital health; wearable devices; electrophysiology study; catheter ablation; ventricular tachycardia; atrial fibrillation; supraventricular tachycardia; syncope

(This special issue belongs to the Section Medical Imaging and Theranostics)

Frontline of Breast Imaging

edited by

Gary J. Whitman

submission deadline 30 Nov 2025 | 5 articles | Viewed by 10486 | Submission Open

Keywords: breast imaging; breast ultrasound; mammography; digital breast tomosynthesis; digital mammography; contrast-enhanced mammography; breast MRI; molecular breast imaging; imaging-guided interventional breast procedures

(This special issue belongs to the Section Medical Imaging and Theranostics)

Sarcoidosis: From Diagnosis to Management

edited by Huzaifa I. Adamali

submission deadline 30 Nov 2025 | 4 articles | Viewed by 10303 | Submission Open

Keywords: sarcoidosis; granulomas; interstitial lung disease; lung; heart; skin; liver; neurological; joints; diagnosis imaging; PET/CT; chest X-ray

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Predictive and Prognostic Markers in Critically Ill Patients, 2nd Edition

edited by

Silvia De Rosa

and Sergio Lassola

submission deadline 30 Nov 2025 | 5 articles | Viewed by 10138 | Submission Open

Keywords: acute brain injury; acute kidney injury; acute mesenteric ischemia; acute pancreatitis; acute respiratory failure; heart failure; infectious disease

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Recent Advances in Clinical Biochemical Testing

edited by

Aw Tar-Choon

submission deadline 30 Nov 2025 | 4 articles | Viewed by 9977 | Submission Open

Keywords: clinical chemistry; diagnostic testing; biomarkers; point-of-care testing; mass spectrometry; immunoassays; microfluidics

(This special issue belongs to the Section Clinical Laboratory Medicine)

Advances in Lung Cancer Diagnosis

edited by

Houssein Youness

submission deadline 30 Nov 2025 | 3 articles | Viewed by 9909 | Submission Open

Keywords: lung cancer; diagnosis; biomarkers; artificial intelligence; machine learning; robotic bronchoscopy; bronchoscopic imaging; endobronchial ultrasound (EBUS); quality indicators; molecular profiling; genetic profiling; next-generation sequencing (NGS); tissue acquisition; low-dose CT screening; early detection; risk assessment; personalized medicine; diagnostic accuracy; medical imaging; lung nodules

(This special issue belongs to the Section Medical Imaging and Theranostics)

Clinical Diagnosis and Management in Orthopaedics and Traumatology

edited by Attilio Basile

submission deadline 30 Nov 2025 | 6 articles | Viewed by 9857 | Submission Open

Keywords: joint replacement; surgical navigation; outcome assessment; fracture repair; imaging technologies

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Eye Imaging

edited by

Antonio Ferreras

submission deadline 30 Nov 2025 | 7 articles | Viewed by 9302 | Submission Open

(This special issue belongs to the Section Medical Imaging and Theranostics)

Microbial Infections and Critical Care Medicine: Diagnosis and Management

edited by Eleni K. Mouloudi,

Serafeim Chrysovalantis Kotoulas

and Eleni Massa

submission deadline 30 Nov 2025 | 5 articles | Viewed by 8677 | Submission Open

Keywords: microbial infections; superbugs; antimicrobial resistance; multi-drug resistance; critical care; diagnosis; management

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Advances in the Diagnosis and Management of Urologic Diseases

edited by

Uroš Bumbaširević

and Otas Durutovic

submission deadline 30 Nov 2025 | 4 articles | Viewed by 7687 | Submission Open

Keywords: urologic diseases; diagnosis; management; urologic oncology; endourology; minimally invasive surgery; urolithiasis

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnosis and Management of Cardiovascular Disorders

edited by Michael Genuardi and

Juan Ortega-legaspi

submission deadline 30 Nov 2025 | 4 articles | Viewed by 7247 | Submission Open

Keywords: cardiovascular disorders; heart failure; hemodynamics; cardiomyopathy

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Updates on Stroke: Diagnosis and Management

edited by Joseph Domenico Gabrieli

submission deadline 30 Nov 2025 | 3 articles | Viewed by 7229 | Submission Open

Keywords: ischemic stroke; atheromatous disease; thrombolysis; machine learning; neurovascular anatomy; imaging; thrombectomy; diagnosis and management; prognosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Application of Diagnostic Tools for Dentistry and Maxillofacial Surgery

edited by

Yiu Yan Leung

submission deadline 30 Nov 2025 | 4 articles | Viewed by 7093 | Submission Open

Keywords: diagnostic tools and technologies in dentistry and maxillofacial surgery; diagnostic accuracy; digital imaging techniques; digital radiography; cone-beam computed tomography (CBCT); CAD/CAM technology

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Fetal Imaging

edited by Eldad Katorza

submission deadline 30 Nov 2025 | 5 articles | Viewed by 6550 | Submission Open

(This special issue belongs to the Section Medical Imaging and Theranostics)

Application of Artificial Intelligence to Advance Individualized Diagnosis and Treatment in Emergency and Critical Care Medicine, 2nd Edition

edited by

Zhongheng Zhang

submission deadline 30 Nov 2025 | 3 articles | Viewed by 6333 | Submission Open

Keywords: critical care; sepsis; artificial intelligence; predictive analytics; clustering; acute kidney injury; emergency medicine; transcriptome

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Diagnostics of Chronic Kidney Disease

edited by

Tomasz Gołębiowski

and

Andrzej Konieczny

submission deadline 30 Nov 2025 | 2 articles | Viewed by 5372 | Submission Open

Keywords: chronic kidney disease; diabetic nephropathy; glomerulonephritis; acid– base disorders; uremic toxin; artificial intelligence; metabolic bone disease; vascular access; arteriovenous fistula; catheter; hemodialysis

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Echocardiography Applications in Cardiovascular Diseases

edited by

Corina Maria Vasile

submission deadline 30 Nov 2025 | 4 articles | Viewed by 5361 | Submission Open

Keywords: echocardiography; congenital heart disease; imaging techniques; artificial intelligence; automatization

(This special issue belongs to the Section Medical Imaging and Theranostics)

Medical Images Segmentation and Diagnosis

edited by

Steven L. Fernandes

submission deadline 30 Nov 2025 | 4 articles | Viewed by 4827 | Submission Open

Keywords: medical images; segmentation; diagnosis; prognosis; AI

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Artificial Intelligence-Driven Radiomics in Medical Diagnosis

edited by

Shara WY Lee

submission deadline 30 Nov 2025 | 5 articles | Viewed by 4747 | Submission Open

Keywords: deep learning; convolutional neural networks (CNNs); medical imaging; diagnostic algorithms; image reconstruction; pattern recognition; predictive modelling; clinical integration; tumour identification; algorithmic transparency; image segmentation; diagnostic accuracy

(This special issue belongs to the Section Medical Imaging and Theranostics)

Explainable Machine Learning in Clinical Diagnostics

edited by

Kai-Chih Pai

submission deadline 30 Nov 2025 | 4 articles | Viewed by 4699 | Submission Open

Keywords: interpretable machine learning (IML); explainable machine learning; clinical medicine; knowledge integration; global/local explanations

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Sarcopenia: Predictive Biomarkers, Clinical Characteristics, and Therapeutic Strategies

edited by Jong Geol Do

submission deadline 30 Nov 2025 | 2 articles | Viewed by 4122 | Submission Open

Keywords: sarcopenia; predictive biomarkers; digital health technologies; interdisciplinary treatment approaches; aging population management

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnostic Advances in Obstetrics and Gynecology, Breast Disease and Women’s Health

edited by Menelaos Zafrakas

submission deadline 30 Nov 2025 | 1 articles | Viewed by 3966 | Submission Open

Keywords: obstetrics; gynecology; maternal– fetal medicine; breast; women’ s health; diagnostics

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Ultrasound Imaging in Medicine in 2025

edited by

Michael Bachmann Nielsen

submission deadline 30 Nov 2025 | 2 articles | Viewed by 3689 | Submission Open

Keywords: 3D ultrasound; blood flow velocity; ultrasonography; contrast-enhanced ultrasound; elasticity imaging; endoscopic ultrasound; intervention

(This special issue belongs to the Section Medical Imaging and Theranostics)

Cardiothoracic Imaging: Recent Techniques and Applications in Diagnostics, Third Edition

edited by

Giacomo Sica

and

Stefania Tamburrini

submission deadline 30 Nov 2025 | 2 articles | Viewed by 3295 | Submission Open

Keywords: emergency; cardiac imaging; thoracic imaging; aorta; MRI; CT; radiomics; artificial intelligence; ILD

(This special issue belongs to the Section Medical Imaging and Theranostics)

Musculoskeletal Imaging 2025, 2nd Edition

edited by Parham Pezeshk

submission deadline 30 Nov 2025 | 2 articles | Viewed by 3159 | Submission Open

Keywords: imaging; radiology; diagnostic; musculoskeletal; artificial intelligence

(This special issue belongs to the Section Medical Imaging and Theranostics)

Application of Artificial Intelligence to Oral Diseases

edited by

Gang Li

submission deadline 30 Nov 2025 | 2 articles | Viewed by 2681 | Submission Open

Keywords: oral disease; artificial intelligence; AI-driven diagnosis; oral radiology; cone beam computed tomography (CBCT)

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

AI-Powered Solutions for Personalized Healthcare Monitoring with Wearables

edited by Kuo-Chung Chu,

Jakir Hossain Bhuiyan Masud

and Ming-Chun Huang

submission deadline 30 Nov 2025 | 2 articles | Viewed by 2679 | Submission Open

Keywords: artificial intelligence; wearable technology; health monitoring; remote patient care; personalized healthcare

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advanced Ultrasound Techniques in Diagnosis

edited by

Laith Riyadh Sultan

submission deadline 30 Nov 2025 | 2 articles | Viewed by 2657 | Submission Open

Keywords: super-resolution imaging; microvascular imaging (MVI); contrast-enhanced ultrasound; AI-guided ultrasound; quantitative analysis; diagnostic imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Bacterial Infections and Antimicrobial Resistance: Diagnosis and Management

edited by

Georgina Tzanakaki

submission deadline 30 Nov 2025 | 3 articles | Viewed by 2435 | Submission Open

Keywords: bacterial infections; antimicrobial resistance (AMR); diagnostic innovations; molecular diagnostics; antimicrobial stewardship; multidrug-resistant pathogens; alternative therapies; artificial intelligence

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Physiological Sound Processing for Medical Diagnostics: Innovations, Challenges, and Applications

edited by

Oliver Faust

and Prabal Datta Barua

submission deadline 30 Nov 2025 | 1 articles | Viewed by 2393 | Submission Open

Keywords: heart sounds; lung sounds; cough analysis; sleep apnea and snoring; wearable devices; explainability and ethical AI; standardization and clinical validation

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Insights into Hereditary Gastrointestinal Cancer

edited by Gautam Naresh Mankaney

submission deadline 30 Nov 2025 | 1 articles | Viewed by 2239 | Submission Open

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Digital Innovation in Salivary Diagnostics for Oral and Systemic Health

edited by

Corina Marilena Cristache

submission deadline 30 Nov 2025 | 1 articles | Viewed by 2185 | Submission Open

Keywords: saliva diagnosis; oral disease; systemic diseases; artificial intelligence; AI driven diagnosis

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Diagnostics Advances in Peripheral Nerve Injuries

edited by

Jean Noël Goubier

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1964 | Submission Open

Keywords: peripheral nerve injuries; diagnosis challenges; magnetic resonance imaging (MRI); electromyography (EMG); brachial plexus injury; nerve trunk lesions; radicular lesions; nerve recovery assessment; advances in nerve imaging; EMG-guided treatment

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Paradigm Shift in the Field of Spinal Diagnosis and Treatment in 2025

edited by

Masato Tanaka

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1943 | Submission Open

Keywords: artificial intelligence; mixed reality; navigation; emerging technologies (robot-assisted surgery); functional MRI; fusion images; new innovative diagnostic tools; scoliosis; adult spinal surgery; spinal tumor; spondylodiscitis; minimally invasive surgery (MIS); aging spine

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis and Prognosis of Thyroid Cancer

edited by

Chang Myeon Song

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1804 | Submission Open

Keywords: thyroid cancer; diagnostic methods; prognostic tools; molecular markers; clinical outcomes; imaging

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Echocardiography in the Intensive Care Unit

edited by

Carlo Caiati

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1626 | Submission Open

Keywords: echocardiography; intensive care unit (ICU); critical care; cardiac function; coronary artery disease; sepsis; shock

(This special issue belongs to the Section Medical Imaging and Theranostics)

New Advances in Thoracic Surgery: Clinical Diagnosis, Treatment, and Prognosis—2nd Edition

edited by

Stefano Elia

submission deadline 30 Nov 2025 | 2 articles | Viewed by 1546 | Submission Open

Keywords: thoracic surgery; lung cancer; pleural diseases; mediastinal malignancies; surgical outcome

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

AI and Big Data in Medical Diagnostics

edited by

Miguel Mascarenhas

, Hélder Cardoso and

Guilherme Macedo

submission deadline 30 Nov 2025 | 2 articles | Viewed by 1488 | Submission Open

Keywords: artificial intelligence; big data; diagnosis; convolutional neural networks; precision medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in the Application of Ultrasound Technology in the Diagnosis of Skin Diseases

edited by

Priscila Giavedoni

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1043 | Submission Open

Keywords: skin ultrasound; cutaneous imaging; inflammatory skin diseases; skin tumors; high-frequency ultrasound; diagnostic imaging; medical imaging; ultrasound-guided procedures; dermatology; skin assessment

(This special issue belongs to the Section Medical Imaging and Theranostics)

Clinical Diagnosis and Prognosis of Steatotic Liver Disease

edited by

Helma Pinchemel Cotrim

submission deadline 30 Nov 2025 | 2 articles | Viewed by 1001 | Submission Open

Keywords: steatotic liver disease— SLD; steatohepatitis; steatosis; diagnosis; prognosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

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