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Bioengineering publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Design and Synthesis of Functional Deuterated Biomaterials

edited by Nageshwar R. Yepuri

submission deadline 20 Jul 2025 | 1 articles | Viewed by 1213 | Submission Open

Keywords: deuterated lipids; deuterated phospholipids; lipid nano particle; lipid nano discs; deuterated fatty acids; deuterated amino acids

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Artificial Intelligence in Dentistry: Innovations, Applications, and Future Perspectives

edited by

Hang Nga Mai

and

Tim Joda

submission deadline 31 Jul 2025 | 10 articles | Viewed by 33681 | Submission Open

Keywords: artificial intelligence; big data in dentistry; explainable AI in dental diagnostics; blockchain in dental data security; natural language processing in dental records; robotics in dentistry; smart dental devices; AI in clinical decision support; automation in dentistry; AI-based diagnostic imaging; AI-supported treatment planning

(This special issue belongs to the Section Biosignal Processing)

Recent Advances in Optical Imaging and Machine Learning in Biomedicine

edited by

Daniel L. Farkas

submission deadline 31 Jul 2025 | 10 articles | Viewed by 18319 | Submission Open

Keywords: optical imaging; machine learning; biomedicine; bioengineering; biophotonics; translational research; interdisciplinary

(This special issue belongs to the Section Biosignal Processing)

Engineering Biodegradable-Implant Materials, 2nd Edition

edited by

Hamdy Ibrahim

submission deadline 31 Jul 2025 | 6 articles | Viewed by 11911 | Submission Open

(This special issue belongs to the Section Regenerative Engineering)

Biomechanics Studies in Ophthalmology

edited by Joseph L. Demer

submission deadline 31 Jul 2025 | 8 articles | Viewed by 11184 | Submission Open

Keywords: eye movements; finite element modeling; glaucoma; myopia; ocular biomechanics; ocular trauma; ocular viscoelasticity; optic neuropathy; strabismus

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Musculoskeletal Function in Health and Disease

edited by Adrian Paul Harrison and Else Marie Bartels

submission deadline 31 Jul 2025 | 3 articles | Viewed by 7149 | Submission Open

Keywords: musculoskeletal disorders; muscle injury; pre-habilitation and rehabilitation; healthcare; wearable technology; quality of life; sport science; sport medicine

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Intelligent Wearable and Implantable Devices for Biomedical Applications

edited by Milad Zamani and

Dante Mantini

submission deadline 31 Jul 2025 | 3 articles | Viewed by 6303 | Submission Open

Keywords: bio-inspired and neuromorphic computation; spiking neural networks; biosensor devices and interface circuits; bioelectronics; biosensors; biotelemetry

(This special issue belongs to the Section Biosignal Processing)

Technological Advances for Gait and Balance Assessment

edited by Alessandro Zampogna,

Silvia Del Din

and

Florenc Demrozi

submission deadline 31 Jul 2025 | 5 articles | Viewed by 5307 | Submission Open

Keywords: novel diagnostic devices and wearable sensors; machine learning and artificial intelligence applications; biomechanical analysis; telemedicine and remote monitoring solutions

(This special issue belongs to the Section Biosignal Processing)

Recent Advancements in Wound Healing and Repair

edited by

Wing Sum Siu

submission deadline 31 Jul 2025 | 3 articles | Viewed by 4742 | Submission Open

Keywords: wound healing; wound repair; bioactive dressings; stem cell therapy; tissue engineering; chronic wounds; biomaterials; imaging technologies; nanoparticles; antibacterial properties; biopolymers; wound dressing; cell and molecular biology

(This special issue belongs to the Section Regenerative Engineering)

Deciphering Medicine: The Role of Explainable Artificial Intelligence in Healthcare Innovations, 2nd Edition

edited by

Mohamed Shehata

and

Mostafa Elhosseini

submission deadline 31 Jul 2025 | 2 articles | Viewed by 3986 | Submission Open

Keywords: deciphering medicine; explainable AI; machine learning; deep learning; medical diagnostics and treatment

(This special issue belongs to the Section Biosignal Processing)

Monitoring and Analysis of Human Biosignals, 3rd Edition

edited by

Antonio Lanata

submission deadline 31 Jul 2025 | 3 articles | Viewed by 3785 | Submission Open

Keywords: biosignal; human body sensing; ECG; EEG; EMG; artificial intelligence

(This special issue belongs to the Section Biosignal Processing)

Recent Progress in Craniofacial Regeneration

edited by

Chengfei Zhang

and

Zhaoming Wu

submission deadline 31 Jul 2025 | 2 articles | Viewed by 3334 | Submission Open

Keywords: craniofacial regeneration; regenerative medicine; tissue engineering; craniofacial stem cells; organoid; biomaterials

(This special issue belongs to the Section Regenerative Engineering)

Computed Tomography for Oral and Maxillofacial Applications

edited by

Soo-Hwan Byun

submission deadline 31 Jul 2025 | 3 articles | Viewed by 2999 | Submission Open

Keywords: CBCT; AI; surgery; maxillofacial; customized; low dosage

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Innovative Bioengineering Paradigms for Cardiac Repair: Cell-Based and Cell-Free Approaches

edited by

Jialiang Liang

and Xingyu He

submission deadline 31 Jul 2025 | 2 articles | Viewed by 2731 | Submission Open

Keywords: cardiac regeneration; cardiac repair; stem cells; tissue engineering; cell transplant; gene delivery; extracellular vesicles; nanotechnology; immunomodulation; lineage reprogramming

(This special issue belongs to the Section Regenerative Engineering)

Advances in Fermentation Technology and Bioprocessing

edited by

Prakash Gangadaran

submission deadline 31 Jul 2025 | 1 articles | Viewed by 2544 | Submission Open

Keywords: fermentation technology; bioprocessing; microorganisms; enzymes; bioreactors; sustainable; bio-based products; metabolic engineering; synthetic biology; omics technologies; process optimization; automation; process control; machine learning; artificial intelligence

(This special issue belongs to the Section Biochemical Engineering)

Medical Imaging Analysis: Current and Future Trends

edited by He Zhao and

Lin Gu

submission deadline 31 Jul 2025 | 3 articles | Viewed by 2328 | Submission Open

Keywords: computer vision; artificial intelligence (AI); multi-modality learning; disease progression monitoring; explainable AI; human-computer interaction

(This special issue belongs to the Section Biosignal Processing)

Insights in Tissue Engineering: Novel Developments, Current Challenges, and Future Perspectives

edited by

Philippe Abdel-Sayed

submission deadline 31 Jul 2025 | 1 articles | Viewed by 1952 | Submission Open

Keywords: bioprinting; organ-on-chip; stem cells; vascularization; regeneration; tissue engineering; scaffold; biomaterials; organoids; ATMP

(This special issue belongs to the Section Regenerative Engineering)

Biomaterials Manufacturing: Experimental and Computational Approaches

edited by

Rashid Jamshidi

Samira Malekmohammadi

, Reza Haqshenas and

Mohammad-Ali Shahbazi

submission deadline 31 Jul 2025 | Viewed by 1797 | Submission Open

Keywords: biomaterial manufacturing; additive manufacturing; 3D printing; electrospinning; polymerization; computational modeling; multiscale modeling; machine learning; artificial intelligence

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Artificial Intelligence-Based Medical Imaging Processing

edited by Xin Meng and Yuxiang Zhou

submission deadline 31 Jul 2025 | 1 articles | Viewed by 1623 | Submission Open

Keywords: artificial intelligence; medical imaging; disease detection and prediction; quantitative analysis; clinical integration; bias resilience; model transparency; precision medicine

(This special issue belongs to the Section Biosignal Processing)

Bioengineering in a Generative AI World

edited by

Yifan Zhao

, Ulas Bagci and Yuxiang Zhou

submission deadline 31 Jul 2025 | 2 articles | Viewed by 1436 | Submission Open

Keywords: generative AI; bioengineering; machine learning; synthetic biology; drug discovery

(This special issue belongs to the Section Biosignal Processing)

Advanced Bioremediation Technologies and Processes—2nd Edition

edited by

Bruna Matturro

and

Laura Lorini

submission deadline 31 Jul 2025 | 1 articles | Viewed by 1318 | Submission Open

Keywords: bioremediation; bioprocesses; circular economy; advanced technologies; contaminated groundwater; contaminated soil; artificial intelligence; machine learning

(This special issue belongs to the Section Biochemical Engineering)

Biomaterials and Technology for Oral and Dental Health

edited by

Gherlone Felice Enrico

and

Giulia Teté

submission deadline 31 Jul 2025 | 1 articles | Viewed by 1139 | Submission Open

Keywords: biomaterials; odontoiatria; oral and dental health

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Physical Therapy and Rehabilitation

edited by

Seong-Gil Kim

and Jin-Seop Kim

submission deadline 31 Jul 2025 | 1 articles | Viewed by 937 | Submission Open

Keywords: physical therapy; rehabilitation; exercise prescription; manual therapy; telerehabilitation; telehealth; virtual reality; wearable devices; musculoskeletal rehabilitation; neurological rehabilitation; post-operative recovery; chronic pain management; injury prevention; multidisciplinary rehabilitation; patient-centered care; personalized rehabilitation; functional recovery; mobility improvement; pain alleviation; mental health in rehabilitation; long-term wellness

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Biomedical Engineering and Biomarkers in Plastic and Reconstructive Surgery Applications

edited by Saif Badran and Matthew Wood

submission deadline 31 Jul 2025 | 1 articles | Viewed by 802 | Submission Open

Keywords: tissue engineering; 3D bioprinting; personalized medicine; metabolic biomarkers; regenerative medicine; advanced biomaterials

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Data Modeling and Algorithms in Biomedical Applications

edited by

Ivan Ganchev Ivanov

submission deadline 31 Jul 2025 | 1 articles | Viewed by 745 | Submission Open

Keywords: computer models; algorithms; biomedical applications; predictive modeling; machine learning; data analysis; data modeling; AI applications

(This special issue belongs to the Section Biosignal Processing)

Diagnostic Tools and Therapeutic Strategies for Hip Diseases

edited by Antonio Capone and

Giuseppe Marongiu

submission deadline 31 Jul 2025 | 1 articles | Viewed by 662 | Submission Open

Keywords: hip disease; coxarthrosis; arthritis; joint inflammatory disease; total hip arthroplasty; hip revision surgery; 3D printing; 3D modeling; advanced diagnostic imaging; tribology; finite element analysis

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Advances in Robotic-Assisted Rehabilitation

edited by

Hongwu Wang

submission deadline 31 Jul 2025 | 1 articles | Viewed by 611 | Submission Open

Keywords: robotics-assisted rehabilitation; neurological rehabilitation robotics; wearable robotics; exoskeletons and assistive robotics; adaptive control in robotics; human– robot interaction; AI and machine learning in rehabilitation; translational studies in rehabilitation robotics; ethical considerations in rehabilitation robotics

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Bioimplants for Cancer Therapy and Regenerative Medicine

edited by Dan Wang

submission deadline 31 Jul 2025 | Viewed by 440 | Submission Open

Keywords: bioimplant and biomaterials; cancer therapy; tissue engineering and regenerative medicine; combination approaches; drug delivery

(This special issue belongs to the Section Regenerative Engineering)

Iron Oxide Particles for Biomedical Applications

edited by Thomas Bonnard

submission deadline 31 Jul 2025 | Viewed by 419 | Submission Open

Keywords: iron oxide; magnetic resonance imaging; magnetic particle imaging; hyperthermia; electromagnetism; magnetic motion

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Recent Progress in Stem Cells and Stem Cell-Derived Biotherapeutics for Regenerative Medicine Applications

edited by

Johnson Rajasingh

and Arghya Paul

submission deadline 31 Jul 2025 | Viewed by 416 | Submission Open

Keywords: stem cells; extracellular vesicles; exosomes; regenerative medicine; induced pluripotent stem cells; disease model; mesenchymal stem cells

(This special issue belongs to the Section Regenerative Engineering)

Development of Microfluidics for Biological and Medical Applications

edited by Abhay Andar

submission deadline 31 Jul 2025 | Viewed by 400 | Submission Open

Keywords: diagnostics; medical devices; biotechnology; bioengineering; cell culture; cell engineering; biomanufacturing; microfabrication; nanofabrication

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Intelligent Nanomaterials and Nanorobots for Disease Diagnosis and Treatment

edited by Wenjun Li

submission deadline 31 Jul 2025 | Viewed by 343 | Submission Open

Keywords: preparation and applications of novel intelligent nanomaterials and nanorobots; driving mode and driving forces for intelligent nanomaterials and nanorobots; drug delivery in complex biological environment and physiological barriers; sensing systems and payload delivery; advanced functionality including internal and external stimuli-responsiveness; switch functionality; optical imaging; magnetic imaging; ultrasound imaging; photoacoustic imaging; radionuclide imaging and biosensors; self-propulsion and controllable navigation; applications disease treatment; including chemotherapy; photothermal therapy; photodynamic therapy; chemodynamic therapy; immunotherapy; and multimodal therapy; targeted therapy of various diseases including cancer; diabetes; inflammatory disorders; and cardiovascular diseases

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Far-Sighted Perspectives of Data Science, AI and Digital Models in Biomedicine

edited by

Marco Roccetti

submission deadline 31 Jul 2025 | Viewed by 326 | Submission Open

Keywords: human data science; human– AI teaming; prescient intelligence; biomedinformatics

(This special issue belongs to the Section Biosignal Processing)

Cognitive Decline and Its Transversality: Potential Mechanisms and Modulators of Disease

edited by

Cinzia Coppola

and

Elisabetta Signoriello

submission deadline 31 Jul 2025 | Viewed by 291 | Submission Open

Keywords: cognitive decline; Alzheimer’ s disease; fronto-temporal lobar degeneration; Lewy body disease; multiple sclerosis; protein misfolding; amyloid; tauopathy; neuroinflammation; microglia; astroglia; synaptopathy; CSF biomarkers; plasmatic biomarkers; micro-RNA or miRNA; long noncoding RNA or lncRNA; heart– brain axis; gut– brain axis; cerebrovascular disease; hippocampal atrophy; structural and functional neuroimaging

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Deep Learning for Medical Applications: Challenges and Opportunities

edited by

Roberta Hlavata

, Robert Hudec and

Patrik Kamencay

submission deadline 31 Jul 2025 | Viewed by 280 | Submission Open

Keywords: deep neural networks; deep learning; machine learning; medical applications; healthcare AI; medical imaging; multimodal data integration; model interpretability

(This special issue belongs to the Section Biosignal Processing)

Advanced Restorative Dental Materials and Implant Technologies

edited by

Elena-Raluca Baciu

Alice Mirela Murariu

and

Gabriela Luminița Gelețu

submission deadline 31 Jul 2025 | Viewed by 227 | Submission Open

Keywords: biomaterials; restorative dentistry; dental implants; patient specific implants; nanotechnology; guided tissue regeneration; digital dentistry; minimally invasive techniques; 3D printing

(This special issue belongs to the Section Regenerative Engineering)

Digital Technologies to Improve Diagnostic Cytopathology: Future Outlook

edited by

Enrico Giarnieri

submission deadline 31 Jul 2025 | 1 articles | Viewed by 201 | Submission Open

Keywords: machine learning; cytopathology; digital cytology; computer-aided diagnosis; virtual reality; natural language process

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

New Sights of AI Tools and Deep Learning in Biomedicine

edited by

Mirpouya Mirmozaffari

submission deadline 31 Jul 2025 | Viewed by 194 | Submission Open

Keywords: artificial intelligence; machine learning; optimization; healthcare management; operation research; biomedicine

(This special issue belongs to the Section Biosignal Processing)

Advancements in Machine Learning for Healthcare: Innovations, Challenges, and Future Directions

edited by

Arianna Scala

submission deadline 31 Jul 2025 | Viewed by 190 | Submission Open

Keywords: machine learning; deep learning; predictive analytics; personalized medicine; explainable AI; federated learning; clinical decision support systems; medical imaging; wearable health monitoring

(This special issue belongs to the Section Biosignal Processing)

Robotics and Virtual Reality for Rehabilitation

edited by

Marcos José Navarro-Santana

submission deadline 31 Jul 2025 | Viewed by 188 | Submission Open

Keywords: rehabilitation technology; wearable robotics; telerehabilitation; virtual reality; artificial intelligence; personalized therapy

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

New Sights of Machine Learning and Digital Models in Biomedicine

edited by Hatem Alhadainy

submission deadline 31 Jul 2025 | Viewed by 175 | Submission Open

Keywords: machine learning; biomedical imaging; predictive modeling; medical data analytics; genomics; precision medicine; bioinformatics; machine learning algorithms; computer-aided diagnosis; imaging analysis; clinical decision support; electronic health records (EHR); disease prediction simulation models; virtual patients; drug discovery; health informatics

(This special issue belongs to the Section Biosignal Processing)

Radiation Imaging and Therapy for Biomedical Engineering

edited by Bharat Guthikonda and Stanley Hoang

submission deadline 31 Jul 2025 | Viewed by 163 | Submission Open

Keywords: radiation imaging; radiation therapy; biomedical engineering; diagnostic technologies; therapeutic innovations

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Advanced Optical Tools for Biomedical Applications

edited by

Quoc-Hung Phan

submission deadline 31 Jul 2025 | Viewed by 155 | Submission Open

Keywords: optical biosensor; biomedical application; surface plasmon resonance; fiber optics; optical imaging; coherence tomography; polarization; cancer; disease

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Wearable Device for Musculoskeletal Disease

edited by Ye(Julie) Li

submission deadline 31 Jul 2025 | Viewed by 145 | Submission Open

Keywords: wearable devices; musculoskeletal diseases; biomechanical sensors; remote rehabilitation; real-time monitoring; injury prediction and prevention

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Deep Learning in Medical Applications: Challenges and Opportunities

edited by Richard Bayford,

Sikandar Ali

and

Ali Hussain

submission deadline 31 Jul 2025 | Viewed by 136 | Submission Open

Keywords: deep learning; medical imaging; healthcare; artificial intelligence

(This special issue belongs to the Section Biosignal Processing)

Advanced Data Processing for Wearable Neurophysiological Monitoring in Real-World Settings

edited by

Vincenzo Ronca

and

Pietro Aricò

submission deadline 31 Jul 2025 | Viewed by 125 | Submission Open

Keywords: wearable neurophysiological signals; artifact removal; real-world monitoring; machine learning for biosignals; human factors; bioinformatics; bioengineering

(This special issue belongs to the Section Biosignal Processing)

Engineering Microalgal Systems for a Greener Future

edited by

Ana Filipa Cruz Esteves

and

Alok Kumar Patel

submission deadline 20 Aug 2025 | 1 articles | Viewed by 1294 | Submission Open

Keywords: artificial intelligence; machine learning; bioprocessing; circular bioeconomy; production value addition; biomass valorization; microalgal cultivation systems; sustainable bioprocessing

(This special issue belongs to the Section Biochemical Engineering)

Current Trends in Robotic Rehabilitation Technology

edited by Serena Filoni,

Raffaello Pellegrino

and

Eduardo Palermo

submission deadline 25 Aug 2025 | Viewed by 835 | Submission Open

Keywords: rehabilitation robotics; machine learning and artificial intelligence; neurological diseases; neuroplasticity; virtual reality for rehabilitation

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Bioengineering Platforms for Drug Delivery

edited by Anam Ahsan

submission deadline 25 Aug 2025 | Viewed by 344 | Submission Open

Keywords: biomaterials; drug delivery; nanotechnology; nanobiotechnology; bioengineering platforms; targeted drug delivery; chemotherapy; bioconjugation; disease management; therapeutic agents

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Stem Cell Bioprocessing

edited by Mariana Petronela Hanga and Eirini Theodosiou

submission deadline 25 Aug 2025 | Viewed by 309 | Submission Open

Keywords: bioprocessing of stem cells; microcarriers; biomaterials; stem cell therapy; cultivated meat; ATMPs; extracellular vesicles

(This special issue belongs to the Section Regenerative Engineering)

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