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Bioengineering publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Artificial Intelligence-Based Medical Imaging Processing

edited by Xin Meng and Yuxiang Zhou

submission deadline 31 Aug 2026 | 15 articles | Viewed by 29035 | Submission Open

Keywords: artificial intelligence; medical imaging; disease detection and prediction; quantitative analysis; clinical integration; bias resilience; model transparency; precision medicine

(This special issue belongs to the Section Biosignal Processing)

Musculoskeletal Function in Health and Disease

edited by Adrian Paul Harrison and Else Marie Bartels

submission deadline 31 Aug 2026 | 7 articles | Viewed by 25978 | Submission Open

Keywords: musculoskeletal disorders; muscle injury; pre-habilitation and rehabilitation; healthcare; wearable technology; quality of life; sport science; sport medicine

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Bioengineering and the Eye—3rd Edition

edited by

Dimitrios Karamichos

submission deadline 31 Aug 2026 | 17 articles | Viewed by 25661 | Submission Open

Keywords: stem cell therapies; functional ocular tissue equivalents; biomaterials; 3D bioprinting; tissue engineering

(This special issue belongs to the Section Regenerative Engineering)

AI Advancements in Healthcare: Medical Imaging and Sensing Technologies, 2nd Edition

edited by

Mohammed A. Al-masni

and Kanghyun Ryu

submission deadline 31 Aug 2026 | 11 articles | Viewed by 21226 | Submission Open

Keywords: biomedical imaging; biosignals; medical image analysis; abnormalities classification and detection; medical image segmentation; medical image reconstruction; medical image denoising; medical image registration; AI in biomedical systems; computer-aided diagnosis systems

(This special issue belongs to the Section Biosignal Processing)

Bioengineering in a Generative AI World

edited by

Yifan Zhao

, Ulas Bagci and Yuxiang Zhou

submission deadline 31 Aug 2026 | 4 articles | Viewed by 15953 | Submission Open

Keywords: generative AI; bioengineering; machine learning; synthetic biology; drug discovery

(This special issue belongs to the Section Biosignal Processing)

Advanced 3D-Printed Biomaterials in Dentistry

edited by Andreas Zenthöfer and Ralf Erber

submission deadline 31 Aug 2026 | 7 articles | Viewed by 11933 | Submission Open

Keywords: additive manufacturing; 3D printing; ceramics; polymer-based materials; bone substitutes

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

AI-Driven Approaches to Diseases Detection and Diagnosis

edited by Yannis Trakadis and

Antonio Brunetti

submission deadline 31 Aug 2026 | 10 articles | Viewed by 9781 | Submission Open

Keywords: AI-driven diagnostics; disease detection; AI-driven treatment selection; precision medicine; +/− patient stratification; machine learning; deep learning; medical imaging; digital biomarkers; clinical decision support

(This special issue belongs to the Section Biosignal Processing)

Insights in Tissue Engineering: Novel Developments, Current Challenges, and Future Perspectives

edited by

Philippe Abdel-Sayed

submission deadline 31 Aug 2026 | 5 articles | Viewed by 9711 | Submission Open

Keywords: bioprinting; organ-on-chip; stem cells; vascularization; regeneration; tissue engineering; scaffold; biomaterials; organoids; ATMP

(This special issue belongs to the Section Regenerative Engineering)

Artificial Intelligence and Wearable Biosensors for Precision Medicine: Integrating Technology

edited by

Matteo Frigerio

submission deadline 31 Aug 2026 | 4 articles | Viewed by 8020 | Submission Open

Keywords: healthcare; gynecology; pelvic floor medicine; pelvic floor rehabilitation; pelvic floor training; laparoscopy; pelvic organ prolapse; urinary incontinence; anal incontinence; overactive bladder; ultrasound; urodynamics; urogynecology; new technologies; pelvic pain; laser; radiofrequency; magnetic stimulation; functional electrical stimulation; biofeedback; vaginal rejuvenation; electronic bladder diaries; sacral neuromodulation; women’s health

(This special issue belongs to the Section Biosignal Processing)

New Trends in Biomechanical Modeling in Musculoskeletal Disorders and Diseases

edited by

Philippe Gorce

submission deadline 31 Aug 2026 | 4 articles | Viewed by 7665 | Submission Open

Keywords: musculoskeletal disorders; musculoskeletal diseases; injury biomechanics; muscle biomechanics dynamic and kinematic modeling; gait and posture; muscle electromyography; motion analysis; postural control and balance; occupational health; occupational ergonomics; sport medicine; sport performance; quality of life

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Neuroimaging Techniques and Applications in Neuroscience

edited by

Md Nasir Uddin

submission deadline 31 Aug 2026 | 5 articles | Viewed by 6512 | Submission Open

Keywords: neuroimaging; brain; MRI; MR angiography; fMRI; PET; machine learning; artificial intelligence; neurological disorders

(This special issue belongs to the Section Biosignal Processing)

Advanced Restorative Dental Materials and Implant Technologies

edited by

Elena-Raluca Baciu

Alice Mirela Murariu

and

Gabriela Luminița Gelețu

submission deadline 31 Aug 2026 | 4 articles | Viewed by 5463 | Submission Open

Keywords: biomaterials; restorative dentistry; dental implants; patient specific implants; nanotechnology; guided tissue regeneration; digital dentistry; minimally invasive techniques; 3D printing

(This special issue belongs to the Section Regenerative Engineering)

Biofabrication of Biologically Realistic Constructs: Needs, Challenges, and Opportunities

edited by Nicanor Ilie Moldovan

submission deadline 31 Aug 2026 | 4 articles | Viewed by 5010 | Submission Open

Keywords: biofabrication; biological realism; bioprinting; cell–biomaterial interaction; tissue engineering; hybrid constructs; clinical translation; in vitro models

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Advances in Polyhydroxyalkanoate (PHA) Production, 5th Edition

edited by

Martin Koller

submission deadline 31 Aug 2026 | 1 articles | Viewed by 4430 | Submission Open

Keywords: polyhydroxyalkanoate (PHA); biopolyesters; bioprocess design; sustainable development

(This special issue belongs to the Section Biochemical Engineering)

AI in Biomedical Image Segmentation, Processing and Analysis

edited by

Toufique Ahmed Soomro

Lihong Zheng

and Mohammad Ali Moni

submission deadline 31 Aug 2026 | 2 articles | Viewed by 3974 | Submission Open

Keywords: artificial intelligence; biomedical imaging; image segmentation; deep learning; medical image processing; radiomics; explainable AI; computer-aided diagnosis

(This special issue belongs to the Section Biosignal Processing)

Wearable Technologies and Health Informatics: Advancements in Bioengineering

edited by

Iqram Hussain

and

Jahowa Islam

submission deadline 31 Aug 2026 | 3 articles | Viewed by 3367 | Submission Open

Keywords: wearable sensors; health monitoring; large language model; electronic health record; flexible sensors; sensors; artificial intelligence; smart healthcare; data privacy; machine learning; sensor applications; energy efficiency; health diagnostics; wearable signal processing (EEG, ECG, EMG, PPG, and IMU); internet of things (IoT); activity recognition; biomedical techniques; sleep medicine; smart grid; data science; smart surveillance

(This special issue belongs to the Section Biosignal Processing)

Advanced Technologies for Orthopedic Repair and Regeneration

edited by

Adriano Braile

Mariantonia Braile

and

Giuseppe Toro

submission deadline 31 Aug 2026 | 4 articles | Viewed by 2928 | Submission Open

Keywords: orthopedic regeneration; 3D printing; bioactive materials; mesenchymal stem cells; smart biomaterials; tissue engineering; predictive modeling; immunoengineering; antimicrobial strategies; personalized implants

(This special issue belongs to the Section Regenerative Engineering)

Advanced Microfluidics for Biomedical Engineering: From Single Cell Analysis to Organ on a Chip

edited by Xueying Zhao

submission deadline 31 Aug 2026 | 2 articles | Viewed by 2477 | Submission Open

Keywords: tumor models; organoids; blood–brain barrier; microfluidics; biosensors; 3D bioprinting; drug response

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Bioengineered Contact Lenses: Therapeutics, Biosensing, and Smart Interfaces

edited by

Ahmed Abass

submission deadline 31 Aug 2026 | 1 articles | Viewed by 2273 | Submission Open

Keywords: contact lenses; vision correction; refractive error; smart contact lenses; drug delivery; biosensors; ocular physiology; corneal biomechanics; tear film; biocompatibility; biomedical engineering; responsive materials; wireless systems; myopia management and control; presbyopia; lens design; ocular surface; clinical applications; advanced manufacturing; digital health; mobile health apps

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Voice Analysis Techniques for Medical Diagnosis

edited by

Shinichi Tokuno

and

Antonio Lanata

submission deadline 31 Aug 2026 | 1 articles | Viewed by 2223 | Submission Open

Keywords: voice biomarker; diagnosis; monitoring; severity assessment

(This special issue belongs to the Section Biosignal Processing)

Machine Learning and Artificial Intelligence for Biomedical Applications, 4th Edition

edited by

Crescenzio Gallo

and

Luca Grilli

submission deadline 31 Aug 2026 | 2 articles | Viewed by 1790 | Submission Open

Keywords: artificial intelligence models; biomedicine; machine learning methods; artificial neural networks; precision medicine; personalized health care

(This special issue belongs to the Section Biosignal Processing)

Advances in Nanomaterials for Biosensing and Biomedical Monitoring

edited by

Elena Dilonardo

submission deadline 31 Aug 2026 | 1 articles | Viewed by 1738 | Submission Open

Keywords: biosensors; nanomaterials; nanobiosensing; biomedical monitoring; interface; detection strategies

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Multiscale Mechanics of Biomaterials

edited by Pengfei Dong,

Linxia Gu

and Yi Hua

submission deadline 31 Aug 2026 | 1 articles | Viewed by 1567 | Submission Open

Keywords: multiscale mechanics; atomic force microscopy; machine learning; biomaterials; finite element method

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Peri-Implant Diseases: Bridging the Gap Between Research and Clinical Daily Practice

edited by

Ana Messias

submission deadline 31 Aug 2026 | 1 articles | Viewed by 1411 | Submission Open

Keywords: peri-implant diseases; peri-implant mucositis; peri-implantitis; soft-tissue; technology; surgical; non-surgical

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Multimodal AI‑Assisted Bioprinting: From Material Selection to Automated Fabrication

edited by Ewa Stodolak-Zych,

Ryszard Tadeusiewicz

and Kamila Rawojć

submission deadline 31 Aug 2026 | 1 articles | Viewed by 1113 | Submission Open

Keywords: 3D bioprinting; artificial intelligence; machine learning; bioink design; tissue engineering; multimodal data; closed-loop fabrication; automated manufacturing

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Innovative Bioengineering Paradigms for Cardiac Repair

edited by

Jialiang Liang

submission deadline 31 Aug 2026 | 1 articles | Viewed by 1072 | Submission Open

Keywords: cardiac tissue engineering; myocardial regeneration; biomaterials; 3D bioprinting; stem cells; organ-on-a-Chip; drug delivery; cell reprogramming; heart failure; translational medicine

(This special issue belongs to the Section Regenerative Engineering)

Advanced Computer Methods and Programs in Biomedicine

edited by Rongjun Ge,

Yuting He

and

Chenchu Xu

submission deadline 31 Aug 2026 | 1 articles | Viewed by 1007 | Submission Open

Keywords: precision medicine; big data; computer science; large language models; algorithms; biomedical signal and image processing; artificial intelligence; machine learning; bioinformatics; virtual reality/augmented reality

(This special issue belongs to the Section Biosignal Processing)

Wearable Sensors and Robotic-Assisted Technologies for Activity Assistance and Gait Rehabilitation

edited by

Chun-Ta Chen

and Xiaoling Hu

submission deadline 31 Aug 2026 | 1 articles | Viewed by 956 | Submission Open

Keywords: wearable sensors; robotic-assisted technology; activity assistance; gait rehabilitation; balance; movement impairment; exoskeleton robot

(This special issue belongs to the Section Biosignal Processing)

Advances in Soft Matter for Healthcare Applications

edited by

Ahmed Abass

submission deadline 31 Aug 2026 | Viewed by 870 | Submission Open

Keywords: soft matter; healthcare applications; hydrogels; drug delivery systems; flexible electronics; tissue engineering; soft robotics; bio-inspired materials; responsive materials; wearable sensors; biomedical devices; smart materials; thermally active materials; hot water bottles; pain management; biocompatible materials; clinical translation

Hot-Melt Extrusion and 3D Printing for Enhanced Drug Delivery

edited by

Sateesh Kumar Vemula

submission deadline 31 Aug 2026 | Viewed by 643 | Submission Open

Keywords: 3D printing in pharmaceutics; additive manufacturing in pharmaceuticals; biodegradable polymers; controlled drug release; devices for drug delivery; hot-melt extrusion (HME); implantable drug delivery systems; personalized medicine; regulatory aspects of 3D-printed dosage forms; solid dispersions

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Artificial Intelligence in Autoimmune Diseases

edited by

Fulvia Ceccarelli

and

Marco Sciandrone

submission deadline 31 Aug 2026 | Viewed by 625 | Submission Open

Keywords: artificial intelligence; autoimmune diseases; machine learning; personalized medicine; predictive analytics

(This special issue belongs to the Section Biosignal Processing)

Bioengineering Approaches in Lung Injury and Repair

edited by

Antonio Matías Esquìnas

submission deadline 31 Aug 2026 | Viewed by 554 | Submission Open

Keywords: bioengineering; lung injury; repair mechanisms; stem cell therapy; biomaterials

(This special issue belongs to the Section Regenerative Engineering)

Biomaterial- and Engineering-Based Approaches for Organoids

edited by Xiuzhi Susan Sun

submission deadline 31 Aug 2026 | Viewed by 528 | Submission Open

Keywords: organoids; biomaterials; tissue engineering; three-dimensional bioprinting; microfluidics; extracellular matrix; disease modeling; regenerative medicine; personalized medicine

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Development and Application of Extracellular Vesicles for Neurodegenerative Diseases

edited by Mangesh Dattu Hade

submission deadline 31 Aug 2026 | Viewed by 468 | Submission Open

Keywords: extracellular vesicles (EVs); neurodegenerative diseases; exosomes; blood–brain barrier; biomarkers; therapeutic nanocarriers

(This special issue belongs to the Section Regenerative Engineering)

Advanced Biomaterials, Coatings, and Techniques: Applications in Medicine—2nd Edition

edited by Yong Hou

submission deadline 31 Aug 2026 | Viewed by 332 | Submission Open

Keywords: biomaterials; coatings; advanced techniques; medical devices; implants; tissue engineering; biocompatibility; 3D printing; nanotechnology; surface modification

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Periodontology and Implant Dentistry: Regenerative Strategies, Digital Workflows and Beyond

edited by

Hua-Hong Chien

and

Guo‐Liang Cheng

submission deadline 31 Aug 2026 | Viewed by 276 | Submission Open

Keywords: regenerative periodontology; digital implant dentistry; biomaterials for tissue engineering; CAD/CAM guided surgery; AI driven treatment planning; 3D printing; digital workflow

(This special issue belongs to the Section Regenerative Engineering)

Engineering Intervertebral Disc Models: From Basic Science to Clinical Practice

edited by Lidija Gradišnik

submission deadline 10 Sep 2026 | 1 articles | Viewed by 12102 | Submission Open

Keywords: intervertebral disc; disc degeneration; cell isolation; cell cultures; in vitro cell models; 3D bioprinting; treatment

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Recent Advances in Artificial Intelligence for Wound Assessment

edited by

Zeyun Yu

and D. M. Anisuzzaman

submission deadline 15 Sep 2026 | 1 articles | Viewed by 1626 | Submission Open

Keywords: artificial intelligence; deep learning; medical image analysis; convolutional neural networks; wound assessment; wound segmentation; wound classification; wound healing prediction; telemedicine; digital health

(This special issue belongs to the Section Biosignal Processing)

Bioengineering for Sustainability

edited by

Lalit Goswami

submission deadline 20 Sep 2026 | Viewed by 364 | Submission Open

Keywords: carbon-based materials; biopolymers; platform chemicals; wastewater treatment; resource recovery; biofuels; carbon capturing; smart agriculture; bioreactors

(This special issue belongs to the Section Biochemical Engineering)

Synergistic Strategies of Engineered Microbes and Biomaterials for Infection and Cancer Therapy

edited by

Jun Liu

and Ruijuan Li

submission deadline 25 Sep 2026 | Viewed by 489 | Submission Open

Keywords: microbes; biomaterials; infection; cancer therapy

Modern Medical Imaging in Disease Diagnosis Applications

edited by

Carlo Cosimo Quattrocchi

and

Marco Parillo

submission deadline 30 Sep 2026 | 5 articles | Viewed by 19904 | Submission Open

Keywords: radiology; diagnostic imaging; contrast media; computed tomography; magnetic resonance imaging; ultrasound; artificial intelligence in medical imaging; radiomics

(This special issue belongs to the Section Biosignal Processing)

Deep Learning in Medical Applications: Challenges and Opportunities

edited by Richard Bayford,

Sikandar Ali

and

Ali Hussain

submission deadline 30 Sep 2026 | 3 articles | Viewed by 14507 | Submission Open

Keywords: deep learning; medical imaging; healthcare; artificial intelligence

(This special issue belongs to the Section Biosignal Processing)

Artificial Intelligence for Computer-Aided Detection in Biomedical Applications, 2nd Edition

edited by

Lawrence Chan

submission deadline 30 Sep 2026 | 10 articles | Viewed by 9712 | Submission Open

Keywords: artificial intelligence; computer-aided detection; CAD; biomedical applications; biomedical engineering; radiology; medical imaging; bioinformatics; deep learning; machine learning; disease diagnosis

(This special issue belongs to the Section Biosignal Processing)

Machine Learning and Artificial Intelligence in Pediatric Healthcare

edited by

Hammad Ashraf Ganatra

submission deadline 30 Sep 2026 | 5 articles | Viewed by 8113 | Submission Open

Keywords: artificial intelligence; machine learning; pediatrics; natural language processing; diagnostics

(This special issue belongs to the Section Biosignal Processing)

Cardiovascular Models and Biomechanics

edited by

Hwa Liang Leo

and

Justin Kok Soon Tan

submission deadline 30 Sep 2026 | 4 articles | Viewed by 8011 | Submission Open

Keywords: vascular mechanics; patient-specific modeling; cardiovascular devices; mechanobiology; experimental methods; computational modeling; machine learning

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Sports Biomechanics and Injury Rehabilitation

edited by

Yifei Yao

submission deadline 30 Sep 2026 | 5 articles | Viewed by 6480 | Submission Open

Keywords: biomechanical analysis; injury prevention; rehabilitation techniques; sports performance; movement optimization

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Regenerative Rehabilitation for Spinal Cord Injury

edited by

Ajay Pal

, George Smith and Andrew J. Spence

submission deadline 30 Sep 2026 | 2 articles | Viewed by 5582 | Submission Open

Keywords: spinal cord injury; rehabilitation; neuromodulation; neural regeneration; neuroprotection; neuroplasticity; functional recovery; activity-based therapy; tissue engineering; neurotrophic factors

(This special issue belongs to the Section Regenerative Engineering)

Technological Advances in Neurorehabilitation

edited by

Susan Duff

and Andria J. Farrens

submission deadline 30 Sep 2026 | 6 articles | Viewed by 4958 | Submission Open

Keywords: assistive technology; neuroimaging; neurorehabilitation; robotics; wearables

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Artificial Intelligence in Dentistry: Innovations, Applications, and Future Perspectives, 2nd Edition

edited by

Hang Nga Mai

and

Tim Joda

submission deadline 30 Sep 2026 | 2 articles | Viewed by 4409 | Submission Open

Keywords: artificial intelligence; big data in dentistry; explainable AI in dental diagnostics; blockchain in dental data security; natural language processing in dental records; robotics in dentistry; smart dental devices; AI in clinical decision support; automation in dentistry; AI-based diagnostic imaging; AI-supported treatment planning

(This special issue belongs to the Section Biosignal Processing)

Optical Imaging for Biomedical Applications, 2nd Edition

edited by

Johannes Dominikus Pallua

submission deadline 30 Sep 2026 | 3 articles | Viewed by 4373 | Submission Open

Keywords: microscopy; digital pathology; infrared spectroscopy; Raman spectroscopy; NIR spectroscopy; hyperspectral imaging; combinations with MRI, X-ray, CT, or micro-CT; advanced imaging techniques and systems; imaging-guided surgery and treatment; artificial intelligence-based computational imaging techniques for biomedical imaging; image processing; photoacoustics; optical coherence tomography

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

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