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Synthesis and In Vitro Antiparasitic Activity of Novel Arylamine Mannich Base-Type Derivatives against Trypanosoma cruzi and Leishmania spp.
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Proceedings 2017, 1(6), 659; doi:10.3390/proceedings1060659

Biological Evaluation of Arylamine Mannich Base Derivatives with Potent In Vivo Activity as Potent Antichagasic Agents

Department of Organic and Pharmaceutical Chemistry, Institute of Tropical Health, Universidad de Navarra, 31008 Pamplona, Spain
Departamento de Parasitología, Instituto de Investigación Biosanitaria (ibs.GRANADA), Hospitales Universitarios de Granada/Universidad de Granada, 18014 Granada, Spain
Department of Pharmacology and Toxicology, Universidad de Navarra, Pamplona 31008, Spain
IdiSNA, Navarra Institute for Health Research, Recinto de Complejo Hospitalario de Navarra, Pamplona 31008, Spain
Department of Pharmaceutical Sciences, Federal University of Rio de Janeiro, Rio de Janeiro 21949-900, Brazil
Presented at the 1st Molecules Medicinal Chemistry Symposium, Barcelona, Spain, 8 September 2017.
Author to whom correspondence should be addressed.
Published: 18 October 2017
(This article belongs to the Proceedings of the 1st Molecules Medicinal Chemistry Symposium)
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Note: In lieu of an abstract, this is an excerpt from the first page.


Chagas disease (CD) is a neglected tropical disease caused by the parasite Trypanosoma cruzi [1]. [...]
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Paucar-Bernabé, R.; Moreno-Viguri, E.; Martín-Escolano, R.; Santivañez-Veliz, M.; Azqueta, A.; Cirauqui, N.; Sánchez-Moreno, M.; Pérez-Silanes, S. Biological Evaluation of Arylamine Mannich Base Derivatives with Potent In Vivo Activity as Potent Antichagasic Agents. Proceedings 2017, 1, 659.

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