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Synthesis and In Vitro Antiparasitic Activity of Novel Arylamine Mannich Base-Type Derivatives against Trypanosoma cruzi and Leishmania spp.
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Proceedings 2017, 1(6), 659; doi:10.3390/proceedings1060659 (registering DOI)

Biological Evaluation of Arylamine Mannich Base Derivatives with Potent In Vivo Activity as Potent Antichagasic Agents

1
Department of Organic and Pharmaceutical Chemistry, Institute of Tropical Health, Universidad de Navarra, 31008 Pamplona, Spain
2
Departamento de Parasitología, Instituto de Investigación Biosanitaria (ibs.GRANADA), Hospitales Universitarios de Granada/Universidad de Granada, 18014 Granada, Spain
3
Department of Pharmacology and Toxicology, Universidad de Navarra, Pamplona 31008, Spain
4
IdiSNA, Navarra Institute for Health Research, Recinto de Complejo Hospitalario de Navarra, Pamplona 31008, Spain
5
Department of Pharmaceutical Sciences, Federal University of Rio de Janeiro, Rio de Janeiro 21949-900, Brazil
Presented at the 1st Molecules Medicinal Chemistry Symposium, Barcelona, Spain, 8 September 2017.
*
Author to whom correspondence should be addressed.
Published: 18 October 2017
(This article belongs to the Proceedings of the 1st Molecules Medicinal Chemistry Symposium)
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Chagas disease (CD) is a neglected tropical disease caused by the parasite Trypanosoma cruzi [1].[...]
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Paucar-Bernabé, R.; Moreno-Viguri, E.; Martín-Escolano, R.; Santivañez-Veliz, M.; Azqueta, A.; Cirauqui, N.; Sánchez-Moreno, M.; Pérez-Silanes, S. Biological Evaluation of Arylamine Mannich Base Derivatives with Potent In Vivo Activity as Potent Antichagasic Agents. Proceedings 2017, 1, 659.

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