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Proceedings 2017, 1(4), 529; doi:10.3390/proceedings1040529

Magnetic Detection Structure for LOC Immunoassays, Multiphysics Simulations and Experimental Results

1
Sorbonne Universités, UR2, L2E (Laboratoire d’Electronique et Electromagnétisme), Paris, France
2
Superconductive Electronics Research Lab, Sharif University of Technology, Tehran, Iran
3
Sorbonne Universités, UPMC, UMR 8235, LISE (Laboratoire d’Interfaces et Systèmes Electrochimiques), Paris, France
4
Institute of Bioelectronics, Peter Grünberg Institute (PGI-8), ForschungsZentrum Jülich (FZJ),Jülich, Germany
Presented at the Eurosensors 2017 Conference, Paris, France, 3–6 September 2017.
*
Author to whom correspondence should be addressed.
Published: 18 August 2017
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Abstract

The aim of this work is to develop a completely integrated Lab-On-Chip (LOC) for easy, rapid and cost-effective immunoassays. The pathogen sensing system is composed of a microfluidic channel surrounded by planar microcoils which are responsible for the emission and the detection of magnetic fields. The system allows the detection and quantification of superparamagnetic beads used for immunoassays in a “sandwich” antigen-antibody configuration. Multiphysics simulations have been achieved and preliminary experimental results have allowed to validate the structure.
Keywords: Lab-on-chip; magnetic detection; pathogen sensing; multiphysics simulations; diagnostic in vitro device; microfluidics. Lab-on-chip; magnetic detection; pathogen sensing; multiphysics simulations; diagnostic in vitro device; microfluidics.
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Rabehi, A.; Garlan, B.; Shanehsazzadeh, F.; Kokabi, H.; Ngo, K.; Krause, H.-J. Magnetic Detection Structure for LOC Immunoassays, Multiphysics Simulations and Experimental Results. Proceedings 2017, 1, 529.

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