Integrated System Based on Thin Film Technologies for Cell-Based Bioluminescence Assays†
AbstractThis work presents a miniaturized lab-on-chip system suitable for monitoring the activity of living cells through the on-chip detection of their bioluminescence emission. The system integrates amorphous silicon diodes, acting as temperature and light sensors, and indium tin oxide film, acting as heater, on a single glass substrate. During its operation, the glass is thermally and optically coupled to the investigated cells and electrically connected to an electronic board, which controls the lab-on-chip temperature and monitors the sensor photocurrents. The proposed lab-on-chip is particularly attractive for the development of portable cell-based biosensors useful for biological activity monitoring as well as for cell cytotoxicity evaluation.
Scifeed alert for new publicationsNever miss any articles matching your research from any publisher
- Get alerts for new papers matching your research
- Find out the new papers from selected authors
- Updated daily for 49'000+ journals and 6000+ publishers
- Define your Scifeed now
Caputo, D.; Petrucci, G.; Fiore, V.D.; Buzzin, A.; Nardecchia, M.; Cevenini, L.; Michelini, E.; Mirasoli, M.; Roda, A.; Lovecchio, N.; Costantini, F.; Nascetti, A.; Cesare, G. Integrated System Based on Thin Film Technologies for Cell-Based Bioluminescence Assays. Proceedings 2017, 1, 513.
Caputo D, Petrucci G, Fiore VD, Buzzin A, Nardecchia M, Cevenini L, Michelini E, Mirasoli M, Roda A, Lovecchio N, Costantini F, Nascetti A, Cesare G. Integrated System Based on Thin Film Technologies for Cell-Based Bioluminescence Assays. Proceedings. 2017; 1(4):513.Chicago/Turabian Style
Caputo, Domenico; Petrucci, Giulia; Fiore, Valeria Di; Buzzin, Alessio; Nardecchia, Marco; Cevenini, Luca; Michelini, Elisa; Mirasoli, Mara; Roda, Aldo; Lovecchio, Nicola; Costantini, Francesca; Nascetti, Augusto; Cesare, Giampiero de. 2017. "Integrated System Based on Thin Film Technologies for Cell-Based Bioluminescence Assays." Proceedings 1, no. 4: 513.