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Condens. Matter 2016, 1(1), 7; doi:10.3390/condmat1010007

Development of Nano-Carbon Biosensors Using Glycan for Host Range Detection of Influenza Virus

1
College of Engineering, Chubu University, 1200 Matsumoto-cho, Kasugai, Aichi 487-8501, Japan
2
College of Life and Health Sciences, Chubu University, 1200 Matsumoto-cho, Kasugai, Aichi 487-8501, Japan
3
Life Science Research Center, Kagawa University, 1750-1 Ikenobe, Miki-cho, Kita-gun, Kagawa 761-0793, Japan
4
Graduate School of Science and Technology, Tokushima University, 2-24 Shinkura-cho, Tokushima 770-8501, Japan
5
Institute of Engineering, Tokyo University of Agriculture and Technology, 2-24-16 Nakacho, Koganei, Tokyo 184-8588, Japan
6
The Institute of Scientific and Industrial Research, Osaka University, 8-1 Mihogaoka, Osaka 567-0047, Japan
7
Faculty of Engineering, Hokkaido University, Kita 13, Nishi 8, Kita-ku, Sapporo, Hokkaido 060-8628, Japan
8
Nissin Electric Co. Ltd., 47 Umezu-Takase-cho, Ukyo-ku, Kyoto 615-8686, Japan
This paper is an extended version of our paper given at the 13th International Conference on Atomically Controlled Surfaces, Interfaces and Nanostructures (ACSIN2016), Rome, Italy, 9–15 October 2016.
*
Author to whom correspondence should be addressed.
Academic Editors: Augusto Marcelli and Antonio Bianconi
Received: 6 October 2016 / Revised: 11 November 2016 / Accepted: 24 November 2016 / Published: 1 December 2016
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Abstract

Nano-carbon materials are promising canidates for applications in high performance devices, including highly sensitive biosensors. We have developed a self-alignment process for nano-carbon field effect transistors (FETs), using a carbon nanowall (CNW)—a nano-carbon materials—to fabricate CNW-FETs. We measured the pH dependence of the device properties. The binding molecules are known to be key components for biosensors. We are concentrating on the development of an influenza virus sensor, because the influenza virus is a major public health problem and a highly sensitive sensor is urgently required. We estimated the size of detected molecules of glycan for influenza viruses using atomic force microscopy. The typical molecule size is around 1 nm, and this may be suitable for electronic detection using a FET structure. View Full-Text
Keywords: self-aligned growth process for carbon nanowalls; nano-carbon biosensors; sugar chains for influenza virus detection self-aligned growth process for carbon nanowalls; nano-carbon biosensors; sugar chains for influenza virus detection
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MDPI and ACS Style

Kawahara, T.; Hiramatsu, H.; Suzuki, Y.; Nakakita, S.-I.; Ohno, Y.; Maehashi, K.; Matsumoto, K.; Okamoto, K.; Matsuba, T.; Utsunomiya, R. Development of Nano-Carbon Biosensors Using Glycan for Host Range Detection of Influenza Virus. Condens. Matter 2016, 1, 7.

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