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Int. J. Neonatal Screen. 2018, 4(1), 3; https://doi.org/10.3390/ijns4010003

Congenital Critical Heart Defect Screening in a Health Area of the Community of Valencia (Spain): A Prospective Observational Study

1
Division of Neonatology, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain
2
Instituto de Investigación Sanitaria La Fe, 46026 Valencia, Spain
3
Division of Neonatology, Hospital Universitario Gregorio Marañón, 28007 Madrid, Spain
*
Author to whom correspondence should be addressed.
Received: 9 November 2017 / Revised: 2 January 2018 / Accepted: 2 January 2018 / Published: 5 January 2018
(This article belongs to the Special Issue Neonatal Screening for Critical Congenital Heart Defects)
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Abstract

Despite the progress in the fetal echocardiographic detection of congenital critical heart defects and neonatal physical examination, a significant number of newborn infants are discharged and readmitted to the hospital in severe condition due to cardiac failure or collapse. The aim of this study was to assess the incidence of undetected critical congenital heart disease (CCHD) by a pulse oximetry-screening program in the maternity wards of hospitals with Perinatal Services in a specific geographic area. This is a prospective observational study performed in in the health area corresponding to the city of Valencia. Eligible infants were consecutively admitted newborn infants in the maternities of the participating hospitals with negative fetal echocardiography after normal physical examination in the delivery room. All patients were screened following a specific pulse oximetry protocol before discharge. A total of 8856 newborn infants were screened. A total of three babies presented with severe congenital cardiac malformation and two babies presented with early onset sepsis. Sensitivity was 100% and specificity was 99.97%, with a positive predictive value of 60% and negative predictive value of 100%. Pulse oximetry screening programs in the early neonatal period constitute a valuable tool to avoid inadvertent hospital discharge of severe cardiac malformations and the subsequent life-threatening complications derived. View Full-Text
Keywords: oxygen saturation; pulse oximetry; critical congenital heart disease; screening; newborn oxygen saturation; pulse oximetry; critical congenital heart disease; screening; newborn
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Cubells, E.; Torres, B.; Nuñez-Ramiro, A.; Sánchez-Luna, M.; Izquierdo, I.; Vento, M. Congenital Critical Heart Defect Screening in a Health Area of the Community of Valencia (Spain): A Prospective Observational Study. Int. J. Neonatal Screen. 2018, 4, 3.

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