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J. Imaging 2018, 4(1), 18; https://doi.org/10.3390/jimaging4010018

Image-Guided Cancer Nanomedicine

1
Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
2
Robert H. Lurie Comprehensive Cancer Center, Chicago, IL 60611, USA
Received: 6 November 2017 / Revised: 3 January 2018 / Accepted: 9 January 2018 / Published: 11 January 2018
(This article belongs to the Special Issue Nanoparticles and Medical Imaging for Image Guided Medicine)
View Full-Text   |   Download PDF [613 KB, uploaded 12 January 2018]   |  

Abstract

Multifunctional nanoparticles with superior imaging properties and therapeutic effects have been extensively developed for the nanomedicine. However, tumor-intrinsic barriers and tumor heterogeneity have resulted in low in vivo therapeutic efficacy. The poor in vivo targeting efficiency in passive and active targeting of nano-therapeutics along with the toxicity of nanoparticles has been a major problem in nanomedicine. Recently, image-guided nanomedicine, which can deliver nanoparticles locally using non-invasive imaging and interventional oncology techniques, has been paid attention as a new opportunity of nanomedicine. This short review will discuss the existing challenges in nanomedicine and describe the prospects for future image-guided nanomedicine. View Full-Text
Keywords: nanomedicine; image; image-guided nanomedicine; nanoparticles; cancer nanomedicine; image; image-guided nanomedicine; nanoparticles; cancer
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).
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Kim, D.-H. Image-Guided Cancer Nanomedicine. J. Imaging 2018, 4, 18.

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