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Gels 2016, 2(4), 28; doi:10.3390/gels2040028

Bioresponsive Hydrogels: Chemical Strategies and Perspectives in Tissue Engineering

Department of Biotechnology and Biosciences, University of Milano-Bicocca, 20126 Milano, Italy
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Academic Editor: Esmaiel Jabbari
Received: 4 August 2016 / Revised: 28 September 2016 / Accepted: 8 October 2016 / Published: 14 October 2016
(This article belongs to the Special Issue Hydrogels in Tissue Engineering)
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Abstract

Disease, trauma, and aging account for a significant number of clinical disorders. Regenerative medicine is emerging as a very promising therapeutic option. The design and development of new cell-customised biomaterials able to mimic extracellular matrix (ECM) functionalities represents one of the major strategies to control the cell fate and stimulate tissue regeneration. Recently, hydrogels have received a considerable interest for their use in the modulation and control of cell fate during the regeneration processes. Several synthetic bioresponsive hydrogels are being developed in order to facilitate cell-matrix and cell-cell interactions. In this review, new strategies and future perspectives of such synthetic cell microenvironments will be highlighted. View Full-Text
Keywords: hydrogels; tissue engineering; bioconjugation hydrogels; tissue engineering; bioconjugation
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Sgambato, A.; Cipolla, L.; Russo, L. Bioresponsive Hydrogels: Chemical Strategies and Perspectives in Tissue Engineering. Gels 2016, 2, 28.

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