Neuro-Immune Mechanisms of Anti-Cryptococcal Protection
Abstract
:1. Introduction
2. Microglia
3. Non-Parenchymal Macrophages
4. Macroglia: Astrocytes and Oligodendrocytes
5. Neurons
6. Brain Microvascular Endothelial Cells (BMECs)
7. T-cells
8. Other Lymphocytes
9. Concluding Remarks
Acknowledgments
Conflicts of Interest
References
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Turnover Rate | Surface Markers | Developmental Transcription Factors | |
---|---|---|---|
Microglia | Long-lived | CD45int CD11b Cx3CR1 Iba-1 Tmem119 MHCIIlow | PU.1 IRF8 CSF1R Sall1 |
Perivascular Macrophages | Long-lived | CD45hi CD11b Cx3CR1 Iba-1 CD163 MHCIIhi CD206 | PU.1 CSF1R |
Choroid Plexus Macrophages | Partial turnover from monocytes | CD45hi CD11b Cx3CR1 Iba-1 MHCIIhi | PU.1 CSF1R |
Meningeal Macrophages | Long-lived | CD45hi CD11b Cx3CR1 Iba-1 MHCIIhi CD206 | PU.1 IRF8 CSF1R |
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Drummond, R.A. Neuro-Immune Mechanisms of Anti-Cryptococcal Protection. J. Fungi 2018, 4, 4. https://doi.org/10.3390/jof4010004
Drummond RA. Neuro-Immune Mechanisms of Anti-Cryptococcal Protection. Journal of Fungi. 2018; 4(1):4. https://doi.org/10.3390/jof4010004
Chicago/Turabian StyleDrummond, Rebecca A. 2018. "Neuro-Immune Mechanisms of Anti-Cryptococcal Protection" Journal of Fungi 4, no. 1: 4. https://doi.org/10.3390/jof4010004