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Bioengineering 2017, 4(2), 28; doi:10.3390/bioengineering4020028

The Separation of Blood Components Using Standing Surface Acoustic Waves (SSAWs) Microfluidic Devices: Analysis and Simulation

1
Biomedical Engineering Department, Faculty of Engineering, Helwan University, Cairo11792, Egypt
2
Communication Department, Faculty of Electronic Engineering, Menoufia University, Menouf 23952, Egypt
*
Author to whom correspondence should be addressed.
Academic Editor: Gou-Jen Wang
Received: 4 February 2017 / Revised: 24 March 2017 / Accepted: 26 March 2017 / Published: 29 March 2017
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Abstract

The separation of blood components (WBCs, RBCs, and platelets) is important for medical applications. Recently, standing surface acoustic wave (SSAW) microfluidic devices are used for the separation of particles. In this paper, the design analysis of SSAW microfluidics is presented. Also, the analysis of SSAW force with Rayleigh angle effect and its attenuation in liquid-loaded substrate, viscous drag force, hydrodynamic force, and diffusion force are explained and analyzed. The analyses are provided for selecting the piezoelectric material, width of the main microchannel, working area of SAW, wavelength, minimum input power required for the separation process, and widths of outlet collecting microchannels. The design analysis of SSAW microfluidics is provided for determining the minimum input power required for the separation process with appropriated the displacement contrast of the particles.The analyses are applied for simulation the separation of blood components. The piezoelectric material, width of the main microchannel, working area of SAW, wavelength, and minimum input power required for the separation process are selected as LiNbO3, 120 μm, 1.08 mm2, 300 μm, 371 mW. The results are compared to other published results. The results of these simulations achieve minimum power consumption, less complicated setup, and high collecting efficiency. All simulation programs are built by MATLAB. View Full-Text
Keywords: surface acoustic waves; microfluidics; separation of blood components; biomedical applications; analysis and simulations surface acoustic waves; microfluidics; separation of blood components; biomedical applications; analysis and simulations
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MDPI and ACS Style

Soliman, A.M.; Eldosoky, M.A.; Taha, T.E. The Separation of Blood Components Using Standing Surface Acoustic Waves (SSAWs) Microfluidic Devices: Analysis and Simulation. Bioengineering 2017, 4, 28.

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